ELECTROCHEMICAL AND ANTIBACTERIAL BEHAVIOR OF DERIVATIVES OF (1S, 2S) - 2 AMINO- 1- (4-NITROPHENYL) - PROPANE-1,3-DIOL

被引:0
|
作者
Cristea, Cecilia [1 ]
Voiculescu, G. [2 ]
Jitaru, Maria [2 ]
Moinet, C. [3 ]
机构
[1] Univ Med & Pharm Iuliu Hatieganu, Fac Pharm, Dept Chim Analyt, 4 Rue Pasteur, Cluj Napoca 400349, Romania
[2] Univ Babes Bolyai Cluj Napoca, Lab Assoc Francophone, Cluj Napoca 400028, Romania
[3] Univ Rennes 1, Inst Chim, Lab Electrochim & Organometall, F-35042 Rennes, France
关键词
electrosynthesis; hydroxylamines; nitrosoderivatives; redox cell;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Derivatives of (1S, 2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol were studied because of their potential biological activity. Using the electrogenerated intermediates (hydroxylamine and nitroso derivatives) N-sulphonylphenylhydroxylamines and benzoxazine diones were obtained with good yields. Their antibacterial activity was investigated on several gram-negative and gram-positive bacilli by two techniques: broth-dilution method and agar-dilution method.
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页码:209 / 216
页数:8
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