DIRECT SYNTHESIS OF 2,6-DISUBSTITUTED PYRIDINES FROM BICYCLIC KETALS

被引：10

作者：

JUN, JG ^{[1
]}

SHIN, HS ^{[1
]}

KIM, SH ^{[1
]}

机构：

[1] KONKUK UNIV, DEPT CHEM, SEOUL, SOUTH KOREA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 15期

关键词：

D O I：

10.1039/p19930001815

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

6,8-Dioxabicyclo[3.2.1]octanes 1, prepared from methyl vinyl ketone dimer, have been readily converted into 2,6-disubstituted pyridine derivatives 2 in one step by treatment with AlCl3-NH2OH.HCl/AcOH. The transformation mechanism of this reaction has been studied by the preparation of a deuterium labelled 1,5-diketone, which was transformed into a pyridine via a dioxime, from the bicyclic ketal.

引用

页码：1815 / 1818

页数：4

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