DIRECT SYNTHESIS OF 2,6-DISUBSTITUTED PYRIDINES FROM BICYCLIC KETALS

被引：10
|
作者：
JUN, JG [1 ]
SHIN, HS [1 ]
KIM, SH [1 ]
机构：
[1] KONKUK UNIV, DEPT CHEM, SEOUL, SOUTH KOREA
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 15期
关键词：
D O I：
10.1039/p19930001815
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
6,8-Dioxabicyclo[3.2.1]octanes 1, prepared from methyl vinyl ketone dimer, have been readily converted into 2,6-disubstituted pyridine derivatives 2 in one step by treatment with AlCl3-NH2OH.HCl/AcOH. The transformation mechanism of this reaction has been studied by the preparation of a deuterium labelled 1,5-diketone, which was transformed into a pyridine via a dioxime, from the bicyclic ketal.
引用
收藏
页码：1815 / 1818
页数：4
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