APICAL EXPRESSION OF HERPES-SIMPLEX VIRUS TYPE-2 GLYCOPROTEINS IN HUMAN NEUROBLASTOMA-CELLS

被引：2
|
作者：
NIELSEN, LN [1 ]
WHITLEY, RJ [1 ]
CHATTERJEE, S [1 ]
机构：
[1] UNIV ALABAMA, DEPT PEDIAT, 988 BASIC HLTH SCI BLDG, BIRMINGHAM, AL 35294 USA
来源：
VIROLOGY | 1991年 / 185卷 / 02期
关键词：
D O I：
10.1016/0042-6822(91)90571-R
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The expression of herpes simplex virus type 2 (HSV-2) glycoproteins on the surface of human neuroblastoma cells has been investigated using Millipore Millicell culture plate inserts. Utilizing a modified radioimmunoassay, we learned that glycoproteins B, C, D, E, and I were expressed predominantly on the apical membrane domain of the infected neuroblastoma cells. The unidirectional transport of HSV-2 glycoproteins was substantiated by the analysis of extracellular glycoproteins released from neuroblastoma cells. The results suggest that the evaluated HSV-2 glycoproteins were transported primarily to the apical plasma membrane domain of human neuroblastoma cells. © 1991.
引用
收藏
页码：908 / 910
页数：3
相关论文
共 50 条
  • [41] AN INVITRO LATENCY SYSTEM FOR HERPES-SIMPLEX VIRUS TYPE-2
    RUSSELL, J
    PRESTON, CM
    JOURNAL OF GENERAL VIROLOGY, 1986, 67 : 397 - 403
  • [42] REMYELINATION IN EXPERIMENTAL HERPES-SIMPLEX VIRUS TYPE-2 INFECTION
    SOFFER, D
    MARTIN, JR
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1986, 45 (03): : 336 - 336
  • [43] REACTIVATION OF TYPE-2 HERPES-SIMPLEX VIRUS BY THORACOLUMBAR NEUROSURGERY
    HAVERKOS, HW
    PAZIN, GJ
    HO, M
    NELSON, PB
    ANNALS OF INTERNAL MEDICINE, 1984, 101 (04) : 503 - 504
  • [44] INHIBITION OF HERPES-SIMPLEX VIRUS TYPE-2 REPLICATION BY THYMIDINE
    COHEN, GH
    FACTOR, MN
    PONCEDEL.M
    JOURNAL OF VIROLOGY, 1974, 14 (01) : 20 - 25
  • [45] HERPES-SIMPLEX VIRUS TYPE-2 AND HIV SEROCONVERSION - REPLY
    KINGSLEY, LA
    ARMSTRONG, JA
    HO, M
    RINALDO, CR
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1991, 4 (07): : 733 - 734
  • [46] STABLE SYNCYTIAL MUTANT OF HERPES-SIMPLEX TYPE-2 VIRUS
    TIMBURY, MC
    THERIAULT, A
    ELTON, RA
    JOURNAL OF GENERAL VIROLOGY, 1974, 23 (MAY): : 219 - 224
  • [47] HERPES-SIMPLEX VIRUS TYPE-2 INFECTION OF NEONATAL MICE
    BAKER, DA
    PLOTKIN, SA
    INFECTION, 1978, 6 (04) : 158 - 161
  • [48] TYPE-2 HERPES-SIMPLEX VIRUS AND VULVAR CARCINOMA INSITU
    SCHWARTZ, PE
    NAFTOLIN, F
    NEW ENGLAND JOURNAL OF MEDICINE, 1981, 305 (09): : 517 - 518
  • [49] XYLOTUBERCIDIN AGAINST HERPES-SIMPLEX VIRUS TYPE-2 IN MICE
    DECLERCQ, E
    ROBINS, MJ
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 30 (05) : 719 - 724
  • [50] A LATENT INFECTION OF HERPES-SIMPLEX VIRUS TYPE-2 IN A HUMAN NEUROBLASTOMA CELL-LINE IMR-32
    YURA, Y
    TERASHIMA, K
    IGA, H
    YANAGAWA, T
    YOSHIDA, H
    HAYASHI, Y
    SATO, M
    ARCHIVES OF VIROLOGY, 1986, 90 (3-4) : 249 - 260
12345