APICAL EXPRESSION OF HERPES-SIMPLEX VIRUS TYPE-2 GLYCOPROTEINS IN HUMAN NEUROBLASTOMA-CELLS

被引：2
|
作者：
NIELSEN, LN [1 ]
WHITLEY, RJ [1 ]
CHATTERJEE, S [1 ]
机构：
[1] UNIV ALABAMA, DEPT PEDIAT, 988 BASIC HLTH SCI BLDG, BIRMINGHAM, AL 35294 USA
来源：
VIROLOGY | 1991年 / 185卷 / 02期
关键词：
D O I：
10.1016/0042-6822(91)90571-R
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The expression of herpes simplex virus type 2 (HSV-2) glycoproteins on the surface of human neuroblastoma cells has been investigated using Millipore Millicell culture plate inserts. Utilizing a modified radioimmunoassay, we learned that glycoproteins B, C, D, E, and I were expressed predominantly on the apical membrane domain of the infected neuroblastoma cells. The unidirectional transport of HSV-2 glycoproteins was substantiated by the analysis of extracellular glycoproteins released from neuroblastoma cells. The results suggest that the evaluated HSV-2 glycoproteins were transported primarily to the apical plasma membrane domain of human neuroblastoma cells. © 1991.
引用
收藏
页码：908 / 910
页数：3
相关论文
共 50 条
  • [21] HERPES-SIMPLEX VIRUS TYPE-2 AND HIV SEROCONVERSION
    HOLMBERG, SD
    GERBER, AR
    STEWART, JA
    BYERS, RH
    NAHMIAS, AJ
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1991, 4 (07): : 732 - 733
  • [22] TYPE-2 HERPES-SIMPLEX VIRUS AND CERVICAL CARCINOMA
    PETERSEN, EE
    BOCKER, JF
    WIMHOFER, G
    ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIES A-MEDICAL MICROBIOLOGY INFECTIOUS DISEASES VIROLOGY PARASITOLOGY, 1974, 227 (1-4): : 356 - 361
  • [23] PERSISTENCE AND EXPRESSION OF HERPES-SIMPLEX VIRUS TYPE-2 GENOME IN CERVICAL TUMOR-CELLS
    AURELIAN, L
    CANCER RESEARCH, 1974, 34 (05) : 1126 - 1135
  • [24] HERPES-SIMPLEX VIRUS AND HUMAN CANCER .1. RELATIONSHIP BETWEEN HUMAN CERVICAL TUMORS AND HERPES-SIMPLEX TYPE-2
    CASSAI, E
    ROTOLA, A
    MENEGUZZI, G
    MILANESI, G
    GARSIA, S
    REMOTTI, G
    RIZZI, G
    EUROPEAN JOURNAL OF CANCER, 1981, 17 (06) : 685 - &
  • [25] EXPRESSION OF HERPES-SIMPLEX VIRUS GLYCOPROTEINS IN POLARIZED EPITHELIAL-CELLS
    SRINIVAS, RV
    BALACHANDRAN, N
    ALONSOCAPLEN, FV
    COMPANS, RW
    JOURNAL OF VIROLOGY, 1986, 58 (02) : 689 - 693
  • [26] SEROEPIDEMIOLOGY OF HERPES-SIMPLEX VIRUS AND RESTRICTION ENDONUCLEASE CLEAVAGE ANALYSIS OF HERPES-SIMPLEX VIRUS TYPE-2 IN OKINAWA
    YOSHITAKE, H
    IWAMASA, T
    MAKINO, Y
    FUKUDA, M
    ACTA PATHOLOGICA JAPONICA, 1991, 41 (01): : 24 - 30
  • [27] ABSENCE OF LEUKOSIS VIRUS MARKERS IN HAMSTER CELLS TRANSFORMED BY HERPES HERPES-SIMPLEX VIRUS TYPE-2
    RAPP, F
    GLASER, R
    CONNER, R
    DUFF, R
    JOURNAL OF VIROLOGY, 1972, 9 (06) : 1059 - &
  • [28] STUDIES ON TUMORS PRODUCED BY CELLS TRANSFORMED WITH HERPES-SIMPLEX VIRUS TYPE-2
    TAKEICHI, S
    OTSUKA, H
    KIMURA, S
    GANN, 1977, 68 (05): : 653 - 661
  • [29] CHARACTERIZATION OF RAT EMBRYO CELLS TRANSFORMED BY HERPES-SIMPLEX VIRUS TYPE-2
    DAWSON, M
    BRAUN, R
    MUNK, K
    ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIES A-MEDICAL MICROBIOLOGY INFECTIOUS DISEASES VIROLOGY PARASITOLOGY, 1983, 254 (02): : 156 - 156
  • [30] CONTROL OF EXPRESSION OF THE HERPES-SIMPLEX VIRUS-INDUCED DEOXYPYRIMIDINE TRIPHOSPHATASE IN CELLS INFECTED WITH MUTANTS OF HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 AND INTERTYPIC RECOMBINANTS
    WOHLRAB, F
    GARRETT, BK
    FRANCKE, B
    JOURNAL OF VIROLOGY, 1982, 43 (03) : 935 - 942
12345