Synthesis of protected alpha-ketoester derivatives using silyl ketene acetals of alkyl dialkoxyacetates

被引：1
|
作者：
Malhiac, C
Tekin, J
Ramiandrasoa, G
Leveque, H
Combret, JC
机构：
[1] Laboratoire de Synthése Hétéroorganique (IRCOF), Université de Rouen
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1995年 / 102卷 / 1-4期
关键词：
1,2,2 trialkoxy-1-trimethylsilyloxyethylene; silyl ketene acetals; aldol-type reactions; protected alpha-ketoester derivatives; nucleophilic synthon C2;
D O I：
10.1080/10426509508042550
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Two readily accessible (RO)(2) C=C(OSiMe(3))(OR) react smoothly with oxygenated electrophiles (aldehydes, ketals, orthoesters) leading, with good yields, to the corresponding beta-functionalized alpha,alpha dialkoxyesters.
引用
收藏
页码：127 / 132
页数：6
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