Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child

被引:4
|
作者
Alyeldien, Ameer [1 ]
Teuber-Hanselmann, Sarah [2 ]
Cheko, Azad [1 ]
Hoell, Tanja [3 ]
Scholz, Martin [1 ]
Petridis, Athanasios K. [4 ]
机构
[1] Sana Kliniken, Dept Neurosurg, Duisburg, Germany
[2] Univ Duisburg Essen, Inst Neuropathol, Essen, Germany
[3] Sana Kliniken, Dept Pediat, Duisburg, Germany
[4] Univ Dusseldorf, Dept Neurosurg, Dusseldorf, Germany
关键词
Pilocytic astrocytoma; metastasis; spinal dissemination; optic chiasm;
D O I
10.4081/cp.2016.813
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pilocytic astrocytomas correspond to low-grade gliomas and therefore metastasize exceedingly rare. However, pilocytic astrocytomas are able to and leptomeningeal dissemination may be seen. What are the treatment options of these cases? We present a case report of a 3-year-old child with a pilocytic astrocytoma of the optic chiasm with leptomeningeal dissemination of the spinal meninges. Partial resection of the cerebral tumor has been performed. Since the leptomeningeal dissemination was seen all over the spinal meninges, the child did not undergo further surgical treatment. A wait and watch strategy were followed. Chemotherapy was initiated, if a 25% tumor growth was seen. Leptomeningeal dissemination of a pilocytic astrocytoma is seen so infrequently that no standard therapy is established. Since these metastases may occur even up to 2 decades after primary tumor resection, long-term follow-up is indicated. In case of spinal metastases, surgical treatment should be performed if feasible. Otherwise observation should be possessed and/ or chemotherapy should be initiated.
引用
收藏
页码:13 / 15
页数:3
相关论文
共 50 条
  • [41] Malignant Hyperthermia in a 3-Year-Old Child With Microstomia
    Evans, Tyler A.
    Flores, Roberto L.
    Tholpady, Sunil S.
    Dierdorf, Stephen
    JOURNAL OF CRANIOFACIAL SURGERY, 2015, 26 (01) : 221 - 223
  • [42] Flomax® Ingestion with Hypotension in a 3-Year-Old Child
    Blume-Odom, C. M.
    Scalzo, A. J.
    Sept, M. F.
    Menendez, J. K.
    Weber, J. A.
    CLINICAL TOXICOLOGY, 2009, 47 (07) : 750 - 750
  • [43] Atypical anaplastic astrocytoma with unique molecular features and diffuse leptomeningeal spread in a child with long-term survival
    Aghajan, Yasmin
    Malicki, Denise M.
    Levy, Michael L.
    Crawford, John Ross
    BMJ CASE REPORTS, 2019, 12 (02)
  • [44] Hypertrichotic nodule on the leg of a 3-year-old child
    Ferrandiz-Pulido, C.
    Ferrer, B.
    Garcia-Patos, V.
    ACTAS DERMO-SIFILIOGRAFICAS, 2010, 101 (04): : 357 - 358
  • [45] Nephrocalcinosis in a 3-year-old child with hypocalcemia: Questions
    Sait, Benazer
    Chidambaram, Aakash Chandran
    Vidhyasagar, Krishnamoorthy
    Babu, Dinesh R. M.
    Sagayaraj, Benjamin
    PEDIATRIC NEPHROLOGY, 2023, 38 (08) : 2563 - 2564
  • [46] PRIMARY PULMONARY HEMANGIOPERICYTOMA IN A 3-YEAR-OLD CHILD
    JOHNSON, JA
    WARREN, ET
    HEATH, BJ
    TEXAS HEART INSTITUTE JOURNAL, 1992, 19 (02) : 146 - 147
  • [47] INTRACTABLE EPISODIC VOMITING IN A 3-YEAR-OLD CHILD
    BERLIN, IN
    MCCULLOUGH, G
    LISKA, ES
    SZUREK, SA
    PSYCHIATRIC QUARTERLY, 1957, 31 (02) : 228 - 249
  • [48] HOW TO EVALUATE LANGUAGE IN THE 3-YEAR-OLD CHILD
    LENORMAND, MT
    SIMON, AM
    FOURNIER, S
    CHEVRIEMULLER, C
    FOLIA PHONIATRICA, 1983, 35 (3-4): : 147 - 147
  • [49] Accidental podophyllin poisoning in a 3-year-old child
    de Wit, T.
    Bisseru, T.
    SOUTH AFRICAN JOURNAL OF CHILD HEALTH, 2015, 9 (02) : 63 - 64
  • [50] Bronchial mucoepidermoid tumor in a 3-year-old child
    J. Anton-Pacheco
    M. A. Jimenez
    J. L. Rodriguez-Peralto
    J. Cuadros
    F. J. Berchi
    Pediatric Surgery International, 1998, 13 : 524 - 525