Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child

被引:4
|
作者
Alyeldien, Ameer [1 ]
Teuber-Hanselmann, Sarah [2 ]
Cheko, Azad [1 ]
Hoell, Tanja [3 ]
Scholz, Martin [1 ]
Petridis, Athanasios K. [4 ]
机构
[1] Sana Kliniken, Dept Neurosurg, Duisburg, Germany
[2] Univ Duisburg Essen, Inst Neuropathol, Essen, Germany
[3] Sana Kliniken, Dept Pediat, Duisburg, Germany
[4] Univ Dusseldorf, Dept Neurosurg, Dusseldorf, Germany
关键词
Pilocytic astrocytoma; metastasis; spinal dissemination; optic chiasm;
D O I
10.4081/cp.2016.813
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pilocytic astrocytomas correspond to low-grade gliomas and therefore metastasize exceedingly rare. However, pilocytic astrocytomas are able to and leptomeningeal dissemination may be seen. What are the treatment options of these cases? We present a case report of a 3-year-old child with a pilocytic astrocytoma of the optic chiasm with leptomeningeal dissemination of the spinal meninges. Partial resection of the cerebral tumor has been performed. Since the leptomeningeal dissemination was seen all over the spinal meninges, the child did not undergo further surgical treatment. A wait and watch strategy were followed. Chemotherapy was initiated, if a 25% tumor growth was seen. Leptomeningeal dissemination of a pilocytic astrocytoma is seen so infrequently that no standard therapy is established. Since these metastases may occur even up to 2 decades after primary tumor resection, long-term follow-up is indicated. In case of spinal metastases, surgical treatment should be performed if feasible. Otherwise observation should be possessed and/ or chemotherapy should be initiated.
引用
收藏
页码:13 / 15
页数:3
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