Molecular pathogenesis of malignant gliomas

被引：0
|
作者：
Van de Kelft, E [1 ]
机构：
[1] Onze Lieve Vrouwe Ziekenhuis, Dept Neurosurg, Aalst, Belgium
来源：
11TH EUROPEAN CONGRESS OF NEUROSURGERY: EUROPEAN ASSOCIATION OF NEUROSURGICAL SOCIETIES (EANS) | 1999年
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Current molecular data, combined with age and clinical onset, distinguish at least two subtypes of glioblastomas: de novo and progressive. However, none of the molecular parameters studied so far have shown significant association with patient survival in this disease. The Ip and 19q allelic losses have significant diagnostic and prognostic importance. As targeted therapy begins to be investigated for gene products, genetic analyses will assume an important role in the treatment of patients with malignant gliomas.
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页码：181 / 192
页数：12
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