RADIOPROTECTIVE EFFECT OF IMMOBILIZED CYSTEMINE

被引：0
|
作者：
BIDZILYA, VA
GOLOVKOVA, LP
BEREGOVSKAYA, NN
BASYUK, VV
KOROL, EN
CHUIKO, AA
ZNAMENSKY, VV
BARKAYA, VS
机构：
来源：
KHIMIKO-FARMATSEVTICHESKII ZHURNAL | 1991年 / 25卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Parameters were defined for adsorption of the two radioprotective agents cystamine and mexamine with pyrogenic silica (the aerosil A-380) and with that containing adsorbed dibenzo-18-crown-6 molecules onto the surface. The formation of aminecrown ether complex on the surface of aerosil was detected by mass spectrometry as a variant of fast atom bombardment. The desorption of cystamine from crown ether-modified aerosil was ascertained to proceed far slowlier than from unmodified one. The found regularities account for the results of biological trials that have established prolongation of effects and increase in radioprotective properties of cystamine and mexamine fixed on the surface of crown ether-modified aerosil.
引用
收藏
页码：25 / 28
页数：4
相关论文
共 50 条
  • [31] PH AND RADIOPROTECTIVE EFFECT OF CYSTEAMINE ON SKIN
    VANCANEGHEM, P
    BEAUMARIAGE, ML
    STRAHLENTHERAPIE, 1973, 145 (06) : 663 - 673
  • [32] THE RADIOPROTECTIVE EFFECT OF AMIFOSTINE ON RAT RETINA
    Ozyigit, G.
    Yildirim, B. Akkus
    Selek, U.
    Yildiz, F.
    Cengiz, M.
    Usubutun, A.
    Uner, A.
    Surucu, S.
    Atahan, L.
    RADIOTHERAPY AND ONCOLOGY, 2008, 88 : S464 - S465
  • [33] RADIOPROTECTIVE EFFECT OF SOME PYRAZOLONE DERIVATIVES
    PISKAREV, AV
    NESTERENKO, VS
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1975, 80 (07) : 782 - 785
  • [34] RADIOPROTECTIVE EFFECT OF SODIUM FLUOROACETATE IN MICE
    NOVAK, L
    SIKULOVA, J
    HOSEK, B
    MISUSTOVA, J
    RADIATION RESEARCH, 1969, 40 (02) : 430 - +
  • [35] Radioprotective effect of a herbal product soma
    Karnaukhova N.A.
    Sergievich L.A.
    Sobruchev S.I.
    Manokhina I.A.
    Rodionov A.V.
    Karnaukhov V.N.
    Biophysics, 2007, 52 (1) : 87 - 91
  • [36] Structural diversity of fucoidans and their radioprotective effect
    Zvyagintseva, Tatiana N.
    Usoltseva, Roza, V
    Shevchenko, Natalia M.
    Surits, Valerii V.
    Imbs, Tatiana I.
    Malyarenko, Olesya S.
    Besednova, Natalia N.
    Ivanushko, Lyudmila A.
    Ermakova, Svetlana P.
    CARBOHYDRATE POLYMERS, 2021, 273 (273)
  • [37] ON THE MECHANISM OF THE RADIOPROTECTIVE EFFECT OF PHENYLHYDRAZINE IN THE MOUSE
    VANCANEGHEM, P
    INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1980, 38 (01) : 119 - 119
  • [38] EVIDENCE FOR A RADIOPROTECTIVE EFFECT OF CHLOROPHYLLIN IN DROSOPHILA
    ZIMMERING, S
    OLVERA, O
    HERNANDEZ, ME
    CRUCES, MP
    ARCEO, C
    PIMENTAL, E
    MUTATION RESEARCH, 1990, 245 (01): : 47 - 49
  • [39] Effect of noradrenaline on radioprotective effect of calcium channel blockers
    Vávrová, J
    Petyrek, P
    FUNDAMENTALS FOR THE ASSESSMENT OF RISKS FROM ENVIRONMENTAL RADIATION, 1999, 55 : 427 - 432
  • [40] RADIOPROTECTIVE EFFECT OF AN ACUTE NONSPECIFIC INFLAMMATION IN MICE
    HERODIN, F
    CALVAS, P
    FATOME, M
    FAUVE, RM
    COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES, 1984, 298 (05): : 113 - &
12345