ERYTHROCYTES SUPPRESS CALCITONIN GENE-RELATED PEPTIDE-LIKE AND VASOACTIVE INTESTINAL POLYPEPTIDE-LIKE IMMUNOREACTIVITIES IN CEREBROVASCULAR NERVE-FIBERS AFTER SUBARACHNOID HEMORRHAGE

被引：6
|
作者：
NOZAKI, K
OKAMOTO, S
UEMURA, Y
KIKUCHI, H
MIZUNO, N
机构：
[1] KYOTO UNIV,FAC MED,DEPT ANAT,KYOTO 606,JAPAN
[2] KYOTO UNIV,FAC MED,DEPT NEUROSURG,KYOTO 606,JAPAN
来源：
NEUROSCIENCE LETTERS | 1990年 / 110卷 / 1-2期
关键词：
Calcitonin gene-related peptide; Cerebral vasospasm; Dog; Immunohistochemistry; Subarachnoid hemorrhage; Vasoactive intestinal polypeptide;
D O I：
10.1016/0304-3940(90)90781-4
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Changes of calcitonin gene related-peptide (CGRP)- and vasoactive intestinal polypeptide (VIP)-like immunoreactivities (LI) in cerebrovascular nerve fibers on the dog basilar artery were immunohistochemically examined by using whole-mount preparations after single percutaneous injection of blood components into the cisterna magna. Blood components were prepared from autologous arterial blood. CGRP-and VIP-LI in cerebrovascular nerve fibers were highly suppressed after the injection of washed erythrocytes, but only moderately after the injection of platelet-rich or platelet-poor plasma. The results suggest that erythrocytes may suppress CGRP- and VIP-LI in cerebrovascular nerve fibers after subarachnoid hemorrhage. © 1990.
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页码：22 / 27
页数：6
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