ERYTHROCYTES SUPPRESS CALCITONIN GENE-RELATED PEPTIDE-LIKE AND VASOACTIVE INTESTINAL POLYPEPTIDE-LIKE IMMUNOREACTIVITIES IN CEREBROVASCULAR NERVE-FIBERS AFTER SUBARACHNOID HEMORRHAGE

被引：6

作者：

NOZAKI, K

OKAMOTO, S

UEMURA, Y

KIKUCHI, H

MIZUNO, N

机构：

[1] KYOTO UNIV,FAC MED,DEPT ANAT,KYOTO 606,JAPAN

[2] KYOTO UNIV,FAC MED,DEPT NEUROSURG,KYOTO 606,JAPAN

来源：

NEUROSCIENCE LETTERS | 1990年 / 110卷 / 1-2期

关键词：

Calcitonin gene-related peptide; Cerebral vasospasm; Dog; Immunohistochemistry; Subarachnoid hemorrhage; Vasoactive intestinal polypeptide;

D O I：

10.1016/0304-3940(90)90781-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Changes of calcitonin gene related-peptide (CGRP)- and vasoactive intestinal polypeptide (VIP)-like immunoreactivities (LI) in cerebrovascular nerve fibers on the dog basilar artery were immunohistochemically examined by using whole-mount preparations after single percutaneous injection of blood components into the cisterna magna. Blood components were prepared from autologous arterial blood. CGRP-and VIP-LI in cerebrovascular nerve fibers were highly suppressed after the injection of washed erythrocytes, but only moderately after the injection of platelet-rich or platelet-poor plasma. The results suggest that erythrocytes may suppress CGRP- and VIP-LI in cerebrovascular nerve fibers after subarachnoid hemorrhage. © 1990.

引用

页码：22 / 27

页数：6

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