Synthesis and pharmacological activity of N-[β-(para-substituted benzoyl)ethyl]isoleucine and -methionine

被引：0
|
作者：
Agababyan A.G. [1 ]
Isakhanyan A.Y. [1 ]
Papoyan O.A. [1 ]
Tumadzhyan A.E. [1 ]
Balasanyan A.S. [1 ]
Gevorgyan G.A. [1 ]
机构：
[1] Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan
来源：
Pharmaceutical Chemistry Journal | 2005年 / 39卷 / 7期
关键词：
Ethyl; Organic Chemistry; Hydrochloride; Methionine; Antiinflammatory Activity;
D O I：
10.1007/s11094-005-0156-2
中图分类号：
学科分类号：
摘要：
A series of N-[β-(p-substituted benzoyl)ethyl]-isoleucine and -methionine derivatives have been synthesized via the alkylation of amino acids with p-substituted β-diethylaminopropiophenone hydrochlorides. Some of the synthesized compounds possess significant antiinflammatory activity. © 2005 Springer Science+Business Media, Inc.
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页码：364 / 366
页数：2
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