Synthesis and pharmacological activity of N-[β-(para-substituted benzoyl)ethyl]isoleucine and -methionine

被引：0

作者：

Agababyan A.G. ^{[1
]}

Isakhanyan A.Y. ^{[1
]}

Papoyan O.A. ^{[1
]}

Tumadzhyan A.E. ^{[1
]}

Balasanyan A.S. ^{[1
]}

Gevorgyan G.A. ^{[1
]}

机构：

[1] Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan

来源：

Pharmaceutical Chemistry Journal | 2005年 / 39卷 / 7期

关键词：

Ethyl; Organic Chemistry; Hydrochloride; Methionine; Antiinflammatory Activity;

D O I：

10.1007/s11094-005-0156-2

中图分类号：

学科分类号：

摘要：

A series of N-[β-(p-substituted benzoyl)ethyl]-isoleucine and -methionine derivatives have been synthesized via the alkylation of amino acids with p-substituted β-diethylaminopropiophenone hydrochlorides. Some of the synthesized compounds possess significant antiinflammatory activity. © 2005 Springer Science+Business Media, Inc.

引用

页码：364 / 366

页数：2

共 50 条

[1] 1,3-DIPOLAR CYCLOADDITIONS OF N-(PARA-SUBSTITUTED BENZYLIDENE) PARA-SUBSTITUTED BENZYLAMINE N-OXIDES WITH TRANS-BIS( PARA-SUBSTITUTED BENZOYL)ETHYLENES AND SUBSTITUENT EFFECTS ON REACTION-RATES
TADA, K
YAMADA, T
TODA, F
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1978, 51 (06) : 1839 - 1843
[2] 1,3-DIPOLAR CYCLOADDITION OF N-(PARA-SUBSTITUTED BENZYLIDENE)-PARA-SUBSTITUTED BENZYLAMINE N-OXIDES WITH TRANS-1,2-BIS(PARA-SUBSTITUTED BENZOYL)-ETHYLENES AND ITS KINETIC STUDY
TADA, K
TODA, F
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1978, 36 (07) : 620 - 624
[3] SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW N-[PARA-(SUBSTITUTED BENZAMIDO)BENZOYL]HYDRAZONES
HUSAIN, MI
AMIR, M
CURRENT SCIENCE, 1985, 54 (22): : 1159 - 1161
[4] ACYLATION OF MESITYLENE BY PARA-SUBSTITUTED BENZOYL CHLORIDES
YULDASHEV, KY
ZHURNAL ORGANICHESKOI KHIMII, 1977, 13 (11): : 2369 - 2372
[5] TRANSMISSION OF SUBSTITUENT EFFECTS IN N-(PARA-SUBSTITUTED PHENYL)-PHTHALIMIDES
HOLIK, M
MATEJKOVA, B
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1990, 55 (01) : 261 - 272
[6] Synthesis of para-substituted styrenes
Langle, S
David-Quillot, F
Abarbri, M
Duchêne, A
TETRAHEDRON LETTERS, 2003, 44 (08) : 1647 - 1649
[7] SYNTHESIS OF PARA-SUBSTITUTED PHENYLGLYOXALS
VENIEN, F
BRAULT, A
KERFANTO, M
COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1968, 266 (24): : 1650 - &
[8] SYNTHESIS AND REACTIONS OF SOME PARA-SUBSTITUTED N-HYDROXYACETANILIDES
CALDER, IC
CACIOLLI, S
AUSTRALIAN JOURNAL OF CHEMISTRY, 1979, 32 (06) : 1301 - 1306
[9] SYNTHESIS OF PARA-SUBSTITUTED BENZYLCYCLOPROPYL KETONES
RAZUS, AC
BARTHA, E
ARVAY, Z
GLATZ, AM
REVUE ROUMAINE DE CHIMIE, 1984, 29 (9-10) : 719 - 725
[10] INVESTIGATIONS ON SYNTHESIS OF PARA-SUBSTITUTED PHENYLTRICHLORMETHYLCARBINOLS
OLSZANOWSKI, A
KARMINSKI, W
PRZEMYSL CHEMICZNY, 1981, 60 (01): : 33 - 35

← 1 2 3 4 5 →