O-GlcNAcylation: A Crucial Regulator in Cancer-Associated Biological Events

被引：0
|
作者：
Zhihong Ran
Lei Zhang
Ming Dong
Yu Zhang
Lulu Chen
Qibin Song
机构：
[1] Three Gorges University,Medical College
[2] Renmin Hospital of Wuhan University,Cancer Center
[3] Guangzhou National Laboratory,Department of Pediatrics, Tongji Hospital, Tongji Medical College
[4] Huazhong University of Science and Technology,undefined
来源：
Cell Biochemistry and Biophysics | 2023年 / 81卷
关键词：
O-GlcNAc; OGT; Cancer; Biological events;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
O-GlcNAcylation, a recently discovered post-translational modification of proteins, plays a crucial role in regulating protein structure and function, and is closely associated with multiple diseases. Research has shown that O-GlcNAcylation is abnormally upregulated in most cancers, promoting disease progression. To elucidate the roles of O-GlcNAcylation in cancer, this review summarizes various cancer-associated biological events regulated by O-GlcNAcylation and the corresponding signaling pathways. This work may provide insights for future studies on the function or underlying mechanisms of O-GlcNAcylation in cancer.
引用
收藏
页码：383 / 394
页数：11
相关论文
共 50 条
  • [11] Role and Function of O-GlcNAcylation in Cancer
    Lee, Jii Bum
    Pyo, Kyoung-Ho
    Kim, Hye Ryun
    CANCERS, 2021, 13 (21)
  • [12] Regulation of cancer metabolism by O-GlcNAcylation
    Li, Zhonghua
    Yi, Wen
    GLYCOCONJUGATE JOURNAL, 2014, 31 (03) : 185 - 191
  • [13] O-GlcNAcylation and metabolic reprograming in cancer
    Jozwiak, Pawel
    Forma, Ewa
    Brys, Magdalena
    Krzeslak, Anna
    FRONTIERS IN ENDOCRINOLOGY, 2014, 5
  • [14] Role of O-GlcNAcylation in cancer biology
    Li, Yuxuan
    Qu, Shuhan
    Jin, Hai
    Jia, Qingge
    Li, Mingyang
    PATHOLOGY RESEARCH AND PRACTICE, 2024, 253
  • [15] O-GlcNAcylation in cancer development and immunotherapy*
    He, Xue-Fen
    Hu, Xiaoli
    Wen, Gao-Jing
    Wang, Zhiwei
    Lin, Wen-Jing
    CANCER LETTERS, 2023, 566
  • [16] Regulation of cancer metabolism by O-GlcNAcylation
    Zhonghua Li
    Wen Yi
    Glycoconjugate Journal, 2014, 31 : 185 - 191
  • [17] Perm1 is a Novel Regulator of O-GlcNAcylation in the Heart
    Sreedevi, Karthi
    Shankar, Thirupura S.
    Yedla, Shreya
    James, Amina
    Arowa, Sumaita
    Zaitsev, Alexey V.
    Saijoh, Yukio
    Drakos, Stavros G.
    Warren, Junco S.
    CIRCULATION, 2022, 146
  • [18] Protein O-GlcNAcylation: A Critical Regulator of the Cellular Response to Stress
    Chatham, John C.
    Marchase, Richard B.
    CURRENT SIGNAL TRANSDUCTION THERAPY, 2010, 5 (01) : 49 - 59
  • [19] Protein O-Glcnacylation: A Critical Regulator of the Cellular Response to Stress
    Chatham, John
    Zou, Luyun
    Not, Laszlo
    Laczy, Boglarka
    Marchase, Richard
    GLYCOBIOLOGY, 2009, 19 (11) : 1300 - 1300
  • [20] Role of O-GlcNAcylation in Breast Cancer Biology
    Kozal, Karolina
    Krzeslak, Anna
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2023, 57 (03) : 183 - 197
12345