Carbon nanotube-based biosensors for DNA structure characterization

被引：0
|
作者：
T. I. Abdullin
O. V. Bondar’
A. A. Rizvanov
I. I. Nikitina
机构：
[1] Kazan State University,Faculty of Biology and Soil Science
[2] Kazan State Medical University,Central Research Laboratory
来源：
Applied Biochemistry and Microbiology | 2009年 / 45卷
关键词：
Apply Biochemistry; Oxidation Current; Potential Sweep Rate; Ultrasonic Shearing; Glassy Carbon Elec;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The possibility of DNA detection using electrodes modified with carbon nanotubes (CNTs) was studied. CNTs facilitate the electrochemical oxidation of DNA guanine nucleotide, which allows direct detection of DNA on a modified electrode. Electrochemical properties of DNA depend on its secondary structure and molecular weight. Denaturation of native DNA improves the adsorption of biopolymer on CNTs and results in an increase in DNA oxidation current on the modified electrode. A similar effect is observed after ultrasonic shearing of DNA or its treatment with Fenton’s reagent due to the fragmentation of biopolymer. Our results demonstrate the feasibility of biosensors based on CNT-modified electrodes for the direct detection and characterization of DNA and DNA damaging factors.
引用
下载
收藏
页码：229 / 232
页数：3
相关论文
共 50 条
  • [21] Carbon nanotube-based DNA biosensor for monitoring phenolic pollutants
    Yanqiong Zheng
    Changzhu Yang
    Wenhong Pu
    Jingdong Zhang
    Microchimica Acta, 2009, 166 : 21 - 26
  • [22] Carbon nanotube-based interconnections
    J. Mittal
    K. L. Lin
    Journal of Materials Science, 2017, 52 : 643 - 662
  • [23] Carbon nanotube-based biosensor
    Wohlstadter, JN
    Wilbur, JL
    Sigal, GB
    Biebuyck, HA
    Billadeau, MA
    Dong, LW
    Fischer, AB
    Gudibande, SR
    Jamieson, SH
    Kenten, JH
    Leginus, J
    Leland, JK
    Massey, RJ
    Wohlstadter, SJ
    ADVANCED MATERIALS, 2003, 15 (14) : 1184 - +
  • [24] Carbon nanotube-based interconnections
    Mittal, J.
    Lin, K. L.
    JOURNAL OF MATERIALS SCIENCE, 2017, 52 (02) : 643 - 662
  • [25] Carbon Nanotube-Based Biosensors Using Fusion Technologies with Biologicals & Chemicals for Food Assessment
    Lee, Jinyoung
    BIOSENSORS-BASEL, 2023, 13 (02):
  • [26] A systematic review on the detection and monitoring of toxic gases using carbon nanotube-based biosensors
    Onyancha, Robert Birundu
    Ukhurebor, Kingsley Eghonghon
    Aigbe, Uyiosa Osagie
    Osibote, Otolorin Adelaja
    Kusuma, Heri Septya
    Darmokoesoemo, Handoko
    Balogun, Vincent Aizebeoje
    SENSING AND BIO-SENSING RESEARCH, 2021, 34
  • [27] Carbon nanotube-based nano-biosensors for detecting heavy metals in the aquatic environment
    Rushikesh L. Chopade
    Pritam P. Pandit
    Varad Nagar
    Vinay Aseri
    Badal Mavry
    Anuj Sharma
    Apoorva Singh
    Rohit Kumar Verma
    Garima Awasthi
    Kumud Kant Awasthi
    Mahipal Singh Sankhla
    Environmental Science and Pollution Research, 2023, 30 (5) : 11199 - 11209
  • [28] Carbon nanotube-based nano-biosensors for detecting heavy metals in the aquatic environment
    Chopade, Rushikesh L.
    Pandit, Pritam P.
    Nagar, Varad
    Aseri, Vinay
    Mavry, Badal
    Sharma, Anuj
    Singh, Apoorva
    Verma, Rohit Kumar
    Awasthi, Garima
    Awasthi, Kumud Kant
    Sankhla, Mahipal Singh
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 30 (05) : 11199 - 11209
  • [29] On the elastic properties of carbon nanotube-based composites: modelling and characterization
    Thostenson, ET
    Chou, TW
    JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2003, 36 (05) : 573 - 582
  • [30] Carbon nanotube based biosensors
    Atashbar, MZ
    Bejcek, B
    Singamaneni, S
    Santucci, S
    PROCEEDINGS OF THE IEEE SENSORS 2004, VOLS 1-3, 2004, : 1048 - 1051
12345