Bioactive constituents obtained from the fruits of Citrus aurantium

被引:0
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作者
Yi Zhang
Peijian Huang
Wei He
Kaunda Joseph Sakah
Jingya Ruan
Zheng Li
Tao Wang
机构
[1] Tianjin University of Traditional Chinese Medicine,Tianjin State Key Laboratory of Modern Chinese Medicine
[2] Tianjin University of Traditional Chinese Medicine,Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine
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关键词
L.; Chemical constituents; Intestine motility; Mouse isolated intestine tissue;
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摘要
Three new compounds, citrusauranosides A (1), B (2), and C (3), along with 22 known compounds (4–25) were obtained from the 70% ethanol–water extract of the fruits of Citrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds, 14, 15, 17 and 23 were firstly obtained from Citrus genus, and the NMR data of 17 is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result, 1, 4–8, and 11 displayed significant inhibitory effects on contraction tension.
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页码:146 / 153
页数:7
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