4-Hydroxy-2-quinolones 113. Synthesis and antitubercular activity of N-R-amides of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8-hexahydroquinoline- 3-carboxylic acid

被引：0

作者：

Ukrainets I.V. ^{[1
]}

Kolesnik E.V. ^{[1
]}

Sidorenko L.V. ^{[1
]}

Gorokhova O.V. ^{[1
]}

Turov A.V. ^{[2
]}

机构：

[1] National Pharmaceutical University

[2] Kiev Taras Shevchenko National University

来源：

Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 03期

关键词：

4-hydroxy-2-oxoquinoline-3-carboxylic acids; Amides; Antitubercular activity; Thermolysis; X-ray structural analysis;

D O I：

10.1007/s10593-007-0049-2

中图分类号：

学科分类号：

摘要：

A preparative method has been developed and the synthesis has been effected of anilides and heterylamides of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8- hexahydroquinoline-3-carboxylic acid. A comparative analysis has been carried out of the structure and antitubercular properties of the synthesized compounds and their analogs unsubstituted in the quinoline nucleus. © 2007 Springer Science+Business Media, Inc.

引用

页码：326 / 333

页数：7

共 50 条

[1] 4-hydroxy-2-quinolones. 113. Synthesis and antituberculous activity of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid N-R-amides
Ukrainets, I. V.
Kolesnik, E. V.
Sidorenko, L. V.
Gorokhova, O. V.
Turov, A. V.
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2007, (03): : 405 - 414
[2] 4-hydroxy-2-quinolones. 95. Synthesis, structure, and antitubercular properties of hetarylamides of 4-hydroxy-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3- carboxylic acid
Ukrainets I.V.
Kolesnik E.V.
Sidorenko L.V.
Gorokhova O.V.
Turov A.V.
Chemistry of Heterocyclic Compounds, 2006, 42 (06) : 765 - 775
[3] 4-hydroxy-2-quinolones. 95. Synthesis, structure, and antituberculous properties of 4-hydroxy-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid hetaryl amides
Ukrainets, I. V.
Kolesnik, E. V.
Sidorenko, L. V.
Gorokhova, O. V.
Turov, A. V.
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2006, (06): : 874 - 886
[4] Synthesis and antiinflammatory and analgesic activity of 2-oxo-1,2,5,6,7,8-hexahydroquinoline-4-carboxylic acid amides
Smirnova T.A.
Gavrilov M.Yu.
Vasilyuk M.V.
Zaks A.S.
Kon'shin M.E.
Pharmaceutical Chemistry Journal, 1999, 33 (1) : 27 - 28
[5] 4-Hydroxy-2-quinolones 171*. Synthesis, isomerism, and antitubercular activity of 1-R-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid alkylidenehydrazides
I. V. Ukrainets
Liu Yangyang
A. A. Tkach
A. V. Turov
O. S. Golovchenko
Chemistry of Heterocyclic Compounds, 2009, 45 : 1335 - 1342
[6] 4-HYDROXY-2-QUINOLONES 171*. SYNTHESIS, ISOMERISM, AND ANTITUBERCULAR ACTIVITY OF 1-R-4-HYDROXY-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ALKYLIDENEHYDRAZIDES
Ukrainets, I. V.
Liu Yangyang
Tkach, A. A.
Turov, A. V.
Golovchenko, O. S.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2009, 45 (11) : 1335 - 1342
[7] 4-hydroxy-2-quinolones -: 139.: Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids
Ukrainets, I. V.
Bereznyakova, N. L.
Turaibei, I. A.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (01) : 50 - 63
[8] 4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids
I. V. Ukrainets
N. L. Bereznyakova
I. A. Turaibei
Chemistry of Heterocyclic Compounds, 2008, 44
[9] 4-Hydroxy-2-quinolones 148. Synthesis and antitubercular activity of 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid N-R-amides
I. V. Ukrainets
A. A. Tkach
L. A. Grinevich
Chemistry of Heterocyclic Compounds, 2008, 44
[10] 4-HYDROXY-2-QUINOLONES .7. SYNTHESIS AND BIOLOGICAL PROPERTIES OF 1-R-3-(BENZIMIDAZOLYL-2)-4-HYDROXY-2-QUINOLONES
UKRAINETS, IV
BEZUGLY, PA
GOROKHOVA, OV
TRESKACH, VI
TUROV, AV
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (01): : 105 - 108

← 1 2 3 4 5 →