Zebrafish xenotransplantation as a tool for in vivo cancer study

被引:0
|
作者
Beibei Zhang
Chao Xuan
Yunxi Ji
Weiming Zhang
Daogang Wang
机构
[1] Mie University Graduate School of Medicine,Department of Clinical Laboratory, The Affiliated Hospital of Medical College
[2] Qingdao University,Department of Gastroenterology
[3] The First Affiliated Hospital of Guangxi University of Chinese Medicine,Department of Oncology
[4] The Affiliated Hospital of Binzhou Medical College,undefined
来源
Familial Cancer | 2015年 / 14卷
关键词
Zebrafish; Xenotransplantation; Cancer;
D O I
暂无
中图分类号
学科分类号
摘要
Zebrafish represents a powerful model for cancer research. Particularly, the xenotransplantation of human cancer cells into zebrafish has enormous potential for further evaluation of cancer progression and drug discovery. Various cancer models have been established in adults, juveniles and embryos of zebrafish. This xenotransplantation zebrafish model provides a unique opportunity to monitor cancer proliferation, tumor angiogenesis, metastasis, self-renewal of cancer stem cells, and drug response in real time in vivo. This review summarizes the use of zebrafish as a model for cancer xenotransplantation, and highlights its advantages and disadvantages.
引用
收藏
页码:487 / 493
页数:6
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