Zebrafish xenotransplantation as a tool for in vivo cancer study

被引：0
|
作者：
Beibei Zhang
Chao Xuan
Yunxi Ji
Weiming Zhang
Daogang Wang
机构：
[1] Mie University Graduate School of Medicine,Department of Clinical Laboratory, The Affiliated Hospital of Medical College
[2] Qingdao University,Department of Gastroenterology
[3] The First Affiliated Hospital of Guangxi University of Chinese Medicine,Department of Oncology
[4] The Affiliated Hospital of Binzhou Medical College,undefined
来源：
Familial Cancer | 2015年 / 14卷
关键词：
Zebrafish; Xenotransplantation; Cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Zebrafish represents a powerful model for cancer research. Particularly, the xenotransplantation of human cancer cells into zebrafish has enormous potential for further evaluation of cancer progression and drug discovery. Various cancer models have been established in adults, juveniles and embryos of zebrafish. This xenotransplantation zebrafish model provides a unique opportunity to monitor cancer proliferation, tumor angiogenesis, metastasis, self-renewal of cancer stem cells, and drug response in real time in vivo. This review summarizes the use of zebrafish as a model for cancer xenotransplantation, and highlights its advantages and disadvantages.
引用
收藏
页码：487 / 493
页数：6
相关论文
共 50 条
  • [21] Zebrafish as a new in vivo model to study angiogenesis in human medullary thyroid cancer
    Gaudenzi, G.
    Cotelli, F.
    Dicitore, A.
    Luca, P.
    Vitale, G.
    WIENER KLINISCHE WOCHENSCHRIFT, 2014, 126 : S152 - S153
  • [22] Quantitative wPhenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation
    Zhang, Beibei
    Shimada, Yasuhito
    Kuroyanagi, Junya
    Umemoto, Noriko
    Nishimura, Yuhei
    Tanaka, Toshio
    PLOS ONE, 2014, 9 (01):
  • [23] Zebrafish as an early stage screening tool to study the systemic circulation of nanoparticulate drug delivery systems in vivo
    Sieber, Sandro
    Grossen, Philip
    Detampel, Pascal
    Siegfried, Salome
    Witzigmann, Dominik
    Huwyler, Jorg
    JOURNAL OF CONTROLLED RELEASE, 2017, 264 : 180 - 191
  • [24] Ex vivo model for xenotransplantation
    Fiane, AE
    Videm, V
    Scholz, T
    Pedersen, T
    Karlsen, H
    Geiran, O
    Foerster, A
    Mollnes, T
    Aasen, AO
    Svennevig, J
    TRANSPLANTATION PROCEEDINGS, 1995, 27 (06) : 3560 - 3561
  • [25] A Novel Tool to Measure Extracellular Glutamate in the Zebrafish Nervous System In Vivo
    MacDonald, Ryan B.
    Kashikar, Nachiket D.
    Lagnado, Leon
    Harris, William A.
    ZEBRAFISH, 2017, 14 (03) : 284 - 286
  • [26] PrP Knockout Zebrafish as a Novel Tool for in vivo Studies of PrP Function
    Fleisch, Valerie C.
    Ritzel, Gary
    Pillay, Laura
    Bujold, Adina R.
    Waskiewicz, Andrew J.
    Allison, W. Ted
    PRION, 2010, 4 (03) : 192 - 192
  • [27] Zebrafish embryo, a tool to study tumor angiogenesis
    Tobia, Chiara
    De Sena, Giulia
    Presta, Marco
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2011, 55 (4-5): : 505 - 509
  • [28] The promise of zebrafish as a chemical screening tool in cancer therapy
    Xie, Xiayang
    Ross, James L.
    Cowell, John K.
    Teng, Yong
    FUTURE MEDICINAL CHEMISTRY, 2015, 7 (11) : 1395 - 1405
  • [29] Zebrafish: A prominent tool for cancer drug screening and discovery
    Srivastava, Saumya
    Guo, Linlin
    Mohanty, Atish
    Nelson, Michael
    Armstrong, Brian
    Kulkarni, Prakash
    Salgia, Ravi
    CANCER RESEARCH, 2020, 80 (16)
  • [30] Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era
    Veinotte, Chansey J.
    Dellaire, Graham
    Berman, Jason N.
    DISEASE MODELS & MECHANISMS, 2014, 7 (07) : 745 - 754
12345