Synthesis and antitumor activity of 3,4,5-substituted 1,2,4-triazoles

被引：0
|
作者：
T. R. Ovsepyan
R. G. Melik-Ogandzhanyan
G. A. Panosyan
F. G. Arsenyan
B. T. Garibdzhanyan
机构：
[1] National Academy of Sciences of Armenia,Mndzhoyan Institute of Fine Organic Chemistry, Molecular Structure Research Center
来源：
Pharmaceutical Chemistry Journal | 2009年 / 43卷
关键词：
synthesis; 1,2,4-triazole; antitumor activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Conditions for effective alkylation of new 3,4-substituted-5-mercapto-1,2,4-triazoles with various alkylating agents are established. Several compounds possessing pronounced antitumor activity have been found in experiments using two xenograft tumor models.
引用
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页码：645 / 648
页数：3
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