Structural insights into the assembly and activation of IL-1β with its receptors

被引：0
|
作者：
Dongli Wang
Senyan Zhang
Liang Li
Xi Liu
Kunrong Mei
Xinquan Wang
机构：
[1] Center for Structural Biology,
[2] School of Life Sciences,undefined
[3] Ministry of Education Key Laboratory of Bioinformatics,undefined
[4] Tsinghua University,undefined
来源：
Nature Immunology | 2010年 / 11卷
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学科分类号：
摘要：
The proinflammatory cytokine IL-1β signals via a heterodimeric receptor composed of the receptor IL-1RI and the accessory protein IL-1RAcP. Wang and colleagues solve the ligand-receptor structure and explain how antagonist interactions differ.
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页码：905 / 911
页数：6
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