A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer

被引：0
|
作者：
Sunjoo Ahn
Dong Jin Hwang
Christina M. Barrett
Jun Yang
Charles B. Duke
Duane D. Miller
James T. Dalton
机构：
[1] The Ohio State University,Division of Pharmaceutics, College of Pharmacy
[2] GTx,Preclinical Research and Development
[3] Inc.,Department of Pharmaceutical Sciences, College of Pharmacy
[4] University of Tennessee,undefined
来源：
Cancer Chemotherapy and Pharmacology | 2011年 / 67卷
关键词：
Indole; Tubulin; Prostate cancer; MDR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：293 / 304
页数：11
相关论文
共 50 条
  • [41] The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus
    Garrison, Aura R.
    Giomarelli, Barbara G.
    Lear-Rooney, Calli M.
    Saucedo, Carrie J.
    Yellayi, Srikanth
    Krumpe, Lauren R. H.
    Rose, Maura
    Paragas, Jason
    Bray, Mike
    Olinger, Gene G., Jr.
    McMahon, James B.
    Huggins, John
    O'Keefe, Barry R.
    [J]. ANTIVIRAL RESEARCH, 2014, 112 : 1 - 7
  • [42] In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B
    Silva, Izabella T.
    Carvalho, Annelise
    Lang, Karen L.
    Dudek, Sabine E.
    Masemann, Doerthe
    Duran, Fernando J.
    Caro, Miguel S. B.
    Rapp, Ulf R.
    Wixler, Viktor
    Schenkel, Eloir P.
    Simoes, Claudia M. O.
    Ludwig, Stephan
    [J]. PLOS ONE, 2015, 10 (02):
  • [43] Gimatecan exerts potent antitumor activity against gastric cancer in vitro and in vivo via AKT and MAPK signaling pathways
    Chen, Zuhua
    Liu, Zhentao
    Huang, Wenwen
    Li, Zhongwu
    Zou, Jianling
    Wang, Jingyuan
    Lin, Xiaoting
    Li, Beifang
    Chen, Dongshao
    Hu, Yanting
    Ji, Jiafu
    Gao, Jing
    Shen, Lin
    [J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2017, 15
  • [44] Gimatecan exerts potent antitumor activity against gastric cancer in vitro and in vivo via AKT and MAPK signaling pathways
    Zuhua Chen
    Zhentao Liu
    Wenwen Huang
    Zhongwu Li
    Jianling Zou
    Jingyuan Wang
    Xiaoting Lin
    Beifang Li
    Dongshao Chen
    Yanting Hu
    Jiafu Ji
    Jing Gao
    Lin Shen
    [J]. Journal of Translational Medicine, 15
  • [45] A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo
    Bemis, DL
    Capodice, JL
    Desai, M
    Buttyan, R
    Katz, AE
    [J]. CLINICAL CANCER RESEARCH, 2004, 10 (15) : 5282 - 5292
  • [46] The Disintegrin Contortrostatin in Combination With Docetaxel Is a Potent Inhibitor of Prostate Cancer In Vitro and In Vivo
    Lin, Edwin
    Wang, Qingcai
    Swenson, Stephen
    Jadvar, Hossein
    Groshen, Susan
    Ye, Wei
    Markland, Francis S.
    Pinski, Jacek
    [J]. PROSTATE, 2010, 70 (12): : 1359 - 1370
  • [47] Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer
    Bandeira Ferreira, Luiz Alberto
    Garcia-Fossa, Fernanda
    Radaic, Allan
    Duran, Nelson
    Favaro, Wagner Jose
    de Jesus, Marcelo Bispo
    [J]. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2020, 151 : 162 - 170
  • [48] Perifosine induces in vitro and in vivo antitumor activity in gastric cancer cells
    Kim, Hyo Song
    Shin, You Keun
    Kim, Tae Soo
    Kim, Jeong Min
    Jeung, Hei-Cheul
    Jang, Woo Ick
    Engel, Juergen
    Chung, Hyun Cheol
    Roh, Jae Kyung
    Rha, Sun Young
    [J]. CANCER RESEARCH, 2012, 72
  • [49] Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo
    Han, Xiqian
    Zhang, Xiaobing
    Li, Hui
    Huang, Shengshi
    Zhang, Shu
    Wang, Fengshan
    Shi, Yikang
    [J]. ONCOTARGET, 2015, 6 (36) : 38912 - 38925
  • [50] A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo
    Jones, Philip
    Altamura, Sergio
    De Francesco, Raffaele
    Paz, Odalys Gonzalez
    Kinzel, Olaf
    Mesiti, Giuseppe
    Monteagudo, Edith
    Pescatore, Giovanna
    Rowley, Michael
    Verdirame, Maria
    Steinkijhler, Christian
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (08) : 2350 - 2353
12345