Gimatecan exerts potent antitumor activity against gastric cancer in vitro and in vivo via AKT and MAPK signaling pathways

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作者
Zuhua Chen
Zhentao Liu
Wenwen Huang
Zhongwu Li
Jianling Zou
Jingyuan Wang
Xiaoting Lin
Beifang Li
Dongshao Chen
Yanting Hu
Jiafu Ji
Jing Gao
Lin Shen
机构
[1] Peking University Cancer Hospital & Institute,Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Oncology
[2] Peking University Cancer Hospital & Institute,Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology
[3] Peking University Cancer Hospital & Institute,Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery
关键词
Gimatecan; Patient-derived xenografts; Gastric cancer; MAPK pathway;
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