Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage Δ6-desaturase

被引:0
|
作者
David Cook
Don Grierson
Craigh Jones
Andrew Wallace
Gill West
Greg Tucker
机构
[1] The University of Nottingham,School of Biosciences, Division of Nutritional Biochemistry, Loughborough
[2] The University of Nottingham,School of Biosciences, Division of Plant Science, Loughborough
来源
Molecular Biotechnology | 2002年 / 21卷
关键词
Tomato; fatty acids; desaturase; nutritional quality; genetic modification;
D O I
暂无
中图分类号
学科分类号
摘要
The improvement of nutritional quality is one potential application for the genetic modification of plants. One possible target for such manipulation is the modification of fatty acid metabolism. In this work, expression of a borage Δ6-desaturase cDNA in tomato (Lycopersicon esculentum L.) has been shown to produce γ-linolenic acid (GLA; 18:3 Δ6,9,12) and octadecatetraenoic acid (OTA; 18:4 Δ6,9,12,15) in transgenic leaf and fruit tissue. This genetic modification has also, unexpectedly, resulted in a reduction in the percentage of linoleic acid (LA 18:2 Δ9,12) and a concomitant increase in the percentage of α-linolenic acid (ALA; 18:3 Δ9,12,15) in fruit tissue. These changes in fatty acid composition are thought to be beneficial for human health.
引用
收藏
页码:123 / 128
页数:5
相关论文
共 50 条
  • [31] Myristic acid increases Δ6-desaturase activity in cultured rat hepatocytes
    Jan, S
    Guillou, H
    D'Andrea, D
    Daval, S
    Bouriel, M
    Rioux, V
    Legrand, P
    REPRODUCTION NUTRITION DEVELOPMENT, 2004, 44 (02): : 131 - 140
  • [32] Conversion of essential fatty acids by delta 6-desaturase in dog liver microsomes
    Dunbar, BL
    Bauer, JE
    JOURNAL OF NUTRITION, 2002, 132 (06): : 1701S - 1703S
  • [33] EXPRESSION OF ACID INVERTASE GENE CONTROLS SUGAR COMPOSITION IN TOMATO (LYCOPERSICON) FRUIT
    KLANN, EM
    CHETELAT, RT
    BENNETT, AB
    PLANT PHYSIOLOGY, 1993, 103 (03) : 863 - 870
  • [34] Resveratrol Modulates Desaturase Expression and Fatty Acid Composition of Cultured Hepatocytes
    Kuehn, Gianna
    Pallauf, Kathrin
    Schulz, Carsten
    Birringer, Marc
    Diaz-Rica, Beatriz
    De Pascual-Teresa, Sonia
    Rimbach, Gerald
    FRONTIERS IN NUTRITION, 2018, 5
  • [36] EFFECT OF APPLICATION OF GIBBERELLIC ACID ON ASCORBIC ACID CONTENT OF TOMATO (LYCOPERSICON ESCULENTUM MILL)
    OZA, AM
    RANGNEKAR, YB
    INDIAN JOURNAL OF AGRICULTURAL SCIENCES, 1969, 39 (10): : 980 - +
  • [37] Co-expression of the borage Δ6 desaturase and the Arabidopsis Δ15 desaturase results in high accumulation of stearidonic acid in the seeds of transgenic soybean
    Eckert, Helene
    LaVallee, Brad
    Schweiger, Bruce J.
    Kinney, Anthony J.
    Cahoon, Edgar B.
    Clemente, Tom
    PLANTA, 2006, 224 (05) : 1050 - 1057
  • [38] Temporal and spatial expression of hexose transporters in developing tomato (Lycopersicon esculentum) fruit
    Dibley, SJ
    Gear, ML
    Yang, X
    Rosche, EG
    Offler, CE
    McCurdy, DW
    Patrick, JW
    FUNCTIONAL PLANT BIOLOGY, 2005, 32 (09) : 777 - 785
  • [39] Disruption of the Fatty Acid Δ6-Desaturase Gene in the Oil-Producing Fungus Mortierella isabellina by Homologous Recombination
    Xuewei Zhang
    Mingchun Li
    Dongsheng Wei
    Xiaomei Wang
    Xue Chen
    Laijun Xing
    Current Microbiology, 2007, 55
  • [40] Disruption of the fatty acid Δ6-desaturase gene in the oil-producing fungus Mortierella isabellina by homologous recombination
    Zhang, Xuewei
    Li, Mingchun
    Wei, Dongsheng
    Wang, Xiaomei
    Chen, Xue
    Xing, Laijun
    CURRENT MICROBIOLOGY, 2007, 55 (02) : 128 - 134