Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias

被引：0
|
作者：
Susumu Minamisawa
Yoji Sato
Myeong-Chan Cho
机构：
[1] Yokohama City University School of Medicine,Department of Physiology
来源：
Experimental & Molecular Medicine | 2004年 / 36卷
关键词：
calcium ATPase; calcium homeostasis; cardiomyopathy; heart failure; phospholamban; ryanodine receptor; sarcoplasmic reticulum;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A growing body of evidence, including studies using genetically engineered mouse models, has shown that Ca2+ cycling and Ca2+ -dependent signaling pathways play a pivotal role in cardiac hypertrophy and heart failure. In addition, recent studies identified that mutations of the genes encoding sarcoplasmic reticulum (SR) proteins cause human cardiomyopathies and lethal ventricular arrhythmias. The regulation of Ca2+ homeostasis via the SR proteins may have potential therapeutic value for heart diseases such as cardiomyopathy, heart failure and arrhythmias.
引用
收藏
页码：193 / 203
页数：10
相关论文
共 50 条
  • [1] Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias
    Minamisawa, S
    Sato, Y
    Cho, MC
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2004, 36 (03): : 193 - 203
  • [2] Calcium Cycling Proteins and Their Association With Heart Failure
    Hadri, L.
    Hajjar, R. J.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2011, 90 (04) : 620 - 624
  • [3] Calcium cycling proteins and heart failure: mechanisms and therapeutics
    Marks, Andrew R.
    JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (01): : 46 - 52
  • [4] Calcium cycling proteins in periparturn cardiomyopathy
    Sweet, Wendy E.
    Grossman-McKee, Alex
    Zohn, Stephen F.
    Moravec, Christine S.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 49 (09) : 89A - 89A
  • [5] Calcium cycling proteins and force-frequency relationship in heart failure
    Hasenfuss, G
    Reinecke, H
    Studer, R
    Pieske, B
    Meyer, M
    Drexler, H
    Just, H
    BASIC RESEARCH IN CARDIOLOGY, 1996, 91 : 17 - 22
  • [6] Alterations in calcium cycling proteins in pediatric vs adult heart failure
    Ivsic, Tomislav
    Sweet, Wendy E.
    Rosenthal, Geoffrey L.
    Duncan, Brian W.
    Boyle, Gerard J.
    Moravec, Christine S.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 49 (09) : 269A - 269A
  • [7] Targeting calcium cycling proteins in heart failure through gene transfer
    del Monte, F
    Hajjar, RJ
    JOURNAL OF PHYSIOLOGY-LONDON, 2003, 546 (01): : 49 - 61
  • [8] Calcium cycling in congestive heart failure
    Hasenfuss, G
    Pieske, B
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2002, 34 (08) : 951 - 969
  • [9] The Role of Calcium Handling in Heart Failure and Heart Failure Associated Arrhythmias
    Johnson, Daniel M.
    Mugelli, Alessandro
    Cerbai, Elisabetta
    FRONTIERS IN PHYSIOLOGY, 2019, 10
  • [10] Atrial Fibrillation Complicated by Heart Failure Induces Distinct Remodeling of Calcium Cycling Proteins
    Lugenbiel, Patrick
    Wenz, Fabian
    Govorov, Katharina
    Schweizer, Patrick A.
    Katus, Hugo A.
    Thomas, Dierk
    PLOS ONE, 2015, 10 (03):
12345