Synthesis of sodium 5-sulfate-ivermectin and disodium 4″,5-disulfate-ivermectin

被引：0
|
作者：
M. A. Shchetinina
E. I. Chernoburova
N. G. Kolotyrkina
M. Kh. Dzhafarov
F. I. Vasilevich
I. V. Zavarzin
机构：
[1] Russian Academy of Sciences,N. D. Zelinsky Institute of Organic Chemistry
[2] K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology,undefined
来源：
Russian Chemical Bulletin | 2018年 / 67卷
关键词：
sulfation; ivermectin; sulfuric acid; acetic anhydride; sodium salt of ivermectin 5-sulfate; disodium salt of ivermectin 4″,5-disulfate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Treatment of ivermectin with sulfuric acid–acetic anhydride in pyridine gives sodium 5-sulfate-ivermectin and disodium 4″,5-disulfate-ivermectin. The synthesized salts are water-soluble compounds with promising antiparasitic activity.
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页码：836 / 839
页数：3
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