Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition

被引：0
|
作者：
Se-Ruo Li
Zhu-Xia Tan
Yuan-Hua Chen
Biao Hu
Cheng Zhang
Hua Wang
Hui Zhao
De-Xiang Xu
机构：
[1] Anhui Medical University,Second Affiliated Hospital
[2] Anhui Medical University,Department of Toxicology
来源：
Respiratory Research | / 20卷
关键词：
Pulmonary fibrosis; Vitamin D deficiency; Epithelial-mesenchymal transition; Bleomycin; Mice;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition
    Yuan Liu
    Bing Liu
    Gu-qin Zhang
    Jing-feng Zou
    Meng-lin Zou
    Zhen-shun Cheng
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2018, 391 : 695 - 704
  • [42] Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation
    Guan, Ruijuan
    Wang, Xia
    Zhao, Xiaomei
    Song, Nana
    Zhu, Jimin
    Wang, Jijiang
    Wang, Jin
    Xia, Chunmei
    Chen, Yonghua
    Zhu, Danian
    Shen, Linlin
    SCIENTIFIC REPORTS, 2016, 6
  • [43] Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway
    Wang, Lu
    Zhang, Pan
    Li, Xinpeng
    Zhang, Yi
    Zhan, Qingyuan
    Wang, Chen
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2019, 11 (04): : 2590 - 2602
  • [44] Sorafenib Ameliorates Renal Fibrosis through Inhibition of TGF-β-Induced Epithelial-Mesenchymal Transition
    Jia, Lining
    Ma, Xiaotao
    Gui, Baosong
    Ge, Heng
    Wang, Li
    Ou, Yan
    Tian, Lifang
    Chen, Zhao
    Duan, Zhaoyang
    Han, Jin
    Fu, Rongguo
    PLOS ONE, 2015, 10 (02):
  • [45] Role of Leukotriene Receptor Antagonist on TGF-β and Smad2 Signaling in Bleomycin Induced Pulmonary Fibrosis.
    Lee, W. Y.
    Lee, B. G.
    Kim, S. T.
    Kim, C. J.
    Seo, H. S.
    Park, H. S.
    Park, J. Y.
    Kim, S. H.
    Yong, S. J.
    Shin, K. C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179
  • [46] Farrerol suppresses epithelial-mesenchymal transition in hepatocellular carcinoma via suppression of TGF-(31/Smad2/3 signaling
    Hao, Yaming
    Long, Zhixiong
    Gu, Xiufeng
    PATHOLOGY RESEARCH AND PRACTICE, 2024, 264
  • [47] TSLP Induces Epithelial-Mesenchymal Transition in Nasal Epithelial Cells From Allergic Rhinitis Patients Through TGF-β1/Smad2/3 Signaling
    Yu, Hong Wei
    Wang, Wei Wei
    Jing, Qian
    Pan, Yong Liang
    AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2023, 37 (06) : 739 - 750
  • [48] Longitudinal assessment of bleomycin-induced pulmonary fibrosis by evaluating TGF-β1/Smad2, Nrf2 signaling and metabolomic analysis in mice
    Washimkar, Kaveri R.
    Tomar, Manendra Singh
    Kulkarni, Chirag
    Verma, Shobhit
    Shrivastava, Ashutosh
    Chattopadhyay, Naibedya
    Mugale, Madhav Nilakanth
    LIFE SCIENCES, 2023, 331
  • [49] The antifibrotic effect of pheretima protein is mediated by the TGF-131/Smad2/3 pathway and attenuates inflammation in bleomycin-induced idiopathic pulmonary fibrosis
    Li, Shuyu
    Yang, Qixin
    Chen, Feilong
    Tian, Linhua
    Huo, Jinhai
    Meng, Yanli
    Tang, Qingfa
    Wang, Weiming
    JOURNAL OF ETHNOPHARMACOLOGY, 2022, 286
  • [50] Nintedanib Reduces Ventilation-Augmented Bleomycin-Induced Epithelial-Mesenchymal Transition And Pulmonary Fibrosis Through Suppressing The Src Pathway
    Li, L-F
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
12345