Structural basis of signal-sequence recognition by the signal recognition particle

被引:0
|
作者
Tobias Hainzl
Shenghua Huang
Gitte Meriläinen
Kristoffer Brännström
A Elisabeth Sauer-Eriksson
机构
[1] Umeå University,Department of Chemistry
[2] Umeå University,Department of Medical Biochemistry and Biophysics
来源
Nature Structural & Molecular Biology | 2011年 / 18卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The signal sequence on nascent peptides is recognized by the signal recognition particle (SRP), with subsequent targeting of the SRP-ribosomal nascent complex to the membrane. The structure of a signal sequence bound to the core SRP is presented, revealing structural changes in the SRP upon signal sequence binding.
引用
收藏
页码:389 / 391
页数:2
相关论文
共 50 条
  • [41] Signal Recognition Particle in Human Diseases
    Kellogg, Morgana K.
    Tikhonova, Elena B.
    Karamyshev, Andrey L.
    FRONTIERS IN GENETICS, 2022, 13
  • [42] SRPDB (Signal Recognition Particle Database)
    Gorodkin, J
    Knudsen, B
    Zwieb, C
    Samuelsson, T
    NUCLEIC ACIDS RESEARCH, 2001, 29 (01) : 169 - 170
  • [43] The Signal Recognition Particle Database (SRPDB)
    Larsen, N
    Zwieb, C
    NUCLEIC ACIDS RESEARCH, 1996, 24 (01) : 80 - 81
  • [44] Protein targeting by the signal recognition particle
    Grudnik, Przemyslaw
    Bange, Gert
    Sinning, Irmgard
    BIOLOGICAL CHEMISTRY, 2009, 390 (08) : 775 - 782
  • [45] THE SIGNAL RECOGNITION PARTICLE DATABASE (SRPDB)
    ZWIEB, C
    LARSEN, N
    NUCLEIC ACIDS RESEARCH, 1994, 22 (17) : 3483 - 3484
  • [46] POLYMYOSITIS AND ANTIBODY TO SIGNAL RECOGNITION PARTICLE
    TARGOFF, IN
    JOHNSON, AE
    MILLER, FW
    CLINICAL RESEARCH, 1988, 36 (03): : A537 - A537
  • [47] FUNCTIONAL DISSECTION OF THE SIGNAL RECOGNITION PARTICLE
    SIEGEL, V
    WALTER, P
    TRENDS IN BIOCHEMICAL SCIENCES, 1988, 13 (08) : 314 - 316
  • [48] Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex
    Marcello Clerici
    Marco Faini
    Lena M. Muckenfuss
    Ruedi Aebersold
    Martin Jinek
    Nature Structural & Molecular Biology, 2018, 25 : 135 - 138
  • [49] SRPDB (Signal Recognition Particle Database)
    Zwieb, C
    Samuelsson, T
    NUCLEIC ACIDS RESEARCH, 2000, 28 (01) : 171 - 172
  • [50] ANTIBODY TO SIGNAL RECOGNITION PARTICLE IN POLYMYOSITIS
    TARGOFF, IN
    JOHNSON, AE
    MILLER, FW
    ARTHRITIS AND RHEUMATISM, 1990, 33 (09): : 1361 - 1370