The signal sequence on nascent peptides is recognized by the signal recognition particle (SRP), with subsequent targeting of the SRP-ribosomal nascent complex to the membrane. The structure of a signal sequence bound to the core SRP is presented, revealing structural changes in the SRP upon signal sequence binding.
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Univ Calif San Francisco, Sch Med, Dept Biochem & Biophys S960, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Med, Dept Biochem & Biophys S960, San Francisco, CA 94143 USA
Stroud, RM
Walter, P
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机构:Univ Calif San Francisco, Sch Med, Dept Biochem & Biophys S960, San Francisco, CA 94143 USA