Improved Neuroprotection with Melatonin-Augmented Hypothermia vs Hypothermia Alone in a Perinatal Asphyxia Model: a Randomized Study

被引：0

作者：

E Powell

S Faulkner

A Bainbridge

A Kereyni

D Kelen

M Chandrasekaran

L Lecky-Thompson

D Price

E Cady

G Raivich

X Golay

N J Robertson

机构：

[1] Institute for Women's Health,

[2] University College London,undefined

[3] Medical Physics and Bioengineering,undefined

[4] UCLH NHS Foundation Trust,undefined

[5] Institute of Neurology,undefined

[6] University College London,undefined

来源：

Pediatric Research | 2011年 / 70卷

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摘要：

Background: Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone, anti-oxidant and cellular pro-survival factor, used safely in children with sleep disorders. Melatonin is beneficial following brain injury in adult animals. It is unknown if melatonin augments hypothermic neuroprotection in the developing brain.

引用

页码：67 / 67

共 45 条

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