Improved Neuroprotection with Melatonin-Augmented Hypothermia vs Hypothermia Alone in a Perinatal Asphyxia Model: a Randomized Study

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作者：
E Powell
S Faulkner
A Bainbridge
A Kereyni
D Kelen
M Chandrasekaran
L Lecky-Thompson
D Price
E Cady
G Raivich
X Golay
N J Robertson
机构：
[1] Institute for Women's Health,
[2] University College London,undefined
[3] Medical Physics and Bioengineering,undefined
[4] UCLH NHS Foundation Trust,undefined
[5] Institute of Neurology,undefined
[6] University College London,undefined
来源：
Pediatric Research | 2011年 / 70卷
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摘要：
Background: Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone, anti-oxidant and cellular pro-survival factor, used safely in children with sleep disorders. Melatonin is beneficial following brain injury in adult animals. It is unknown if melatonin augments hypothermic neuroprotection in the developing brain.
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页码：67 / 67
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