user

Precision medicine for cancer with next-generation functional diagnostics

被引：0
|
作者：
Adam A. Friedman
Anthony Letai
David E. Fisher
Keith T. Flaherty
机构：
[1] Massachusetts General Hospital Cancer Center,
[2] Harvard Medical School,undefined
[3] Dermatology and Cutaneous Biology Research Center,undefined
[4] Massachusetts General Hospital,undefined
[5] Dana-Farber Cancer Institute,undefined
[6] Harvard Medical School,undefined
来源：
Nature Reviews Cancer | 2015年 / 15卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Genome-based cancer therapeutic matching is limited by incomplete biological understanding of the relationship between phenotype and cancer genotype. This Opinion article proposes that this limitation can be addressed by functional testing of live patient tumour cells exposed to potential therapies.
引用
收藏
页码：747 / 756
页数：9
相关论文
共 50 条
  • [21] Next-generation sequencing improves precision medicine in hearing loss
    Imizcoz, T.
    Prieto-Matos, C.
    Manrique-Huarte, R.
    Calavia, D.
    Huarte, A.
    Pruneda, P. C.
    Ordonez, G. R.
    Canada-Higueras, E.
    Patino-Garcia, A.
    Alkorta-Aranburu, G.
    Manrique Rodriguez, M.
    FRONTIERS IN GENETICS, 2023, 14
  • [22] Integrating next-generation sequencing into clinical cancer diagnostics
    Chan, Maurice
    Lee, Charlie W-H
    Wu, Mengchu
    EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2013, 13 (07) : 647 - 650
  • [23] Next-Generation sequencing transforming clinical practice and precision medicine
    Yadav, Deepali
    Patil-Takbhate, Bhagyashri
    Khandagale, Anil
    Bhawalkar, Jitendra
    Tripathy, Srikanth
    Khopkar-Kale, Priyanka
    CLINICA CHIMICA ACTA, 2023, 551
  • [24] Next-generation diagnostics with CRISPR
    Chertow, Daniel S.
    SCIENCE, 2018, 360 (6387) : 381 - 382
  • [25] Next-Generation Diagnostics for Pathogens
    Wilkes, Rebecca P.
    VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE, 2023, 39 (01) : 165 - 173
  • [26] Precision Medicine and Precision Public Health in the Era of Pathogen Next-Generation Sequencing
    Leguia, Mariana
    Vila-Sanjurjo, Anton
    Chain, Patrick S. G.
    Berry, Irina Maljkovic
    Jarman, Richard G.
    Pollett, Simon
    JOURNAL OF INFECTIOUS DISEASES, 2020, 221 : S289 - S291
  • [27] Next-Generation Medicine
    Marx-Stoelting, Lilian
    ETHIK IN DER MEDIZIN, 2020, 32 (01) : 115 - 116
  • [28] Next-Generation Cancer Phenomics: A Transformative Approach to Unraveling Lung Cancer Complexity and Advancing Precision Medicine
    Dasgupta, Sanjukta
    OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 2024, 28 (12) : 585 - 595
  • [29] Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer
    Malgerud, Linnea
    Lindberg, Johan
    Wirta, Valtteri
    Gustafsson-Liljefors, Maria
    Karimi, Masoud
    Moro, Carlos Fernandez
    Stecker, Katrin
    Picker, Alexander
    Huelsewig, Carolin
    Stein, Martin
    Bohnert, Regina
    Del Chiaro, Marco
    Haas, Stephan L.
    Heuchel, Rainer L.
    Permert, Johan
    Maeurer, Markus J.
    Brock, Stephan
    Verbeke, Caroline S.
    Engstrand, Lars
    Jackson, David B.
    Gronberg, Henrik
    Lohr, Johannes-Matthias
    MOLECULAR ONCOLOGY, 2017, 11 (10) : 1413 - 1429
  • [30] Next-Generation Sequencing in Breast Cancer Patients: Real-World Data for Precision Medicine
    Lee, Hyunwoo
    Cho, Yoon Ah
    Kim, Deok Geun
    Cho, Eun Yoon
    CANCER RESEARCH AND TREATMENT, 2024, 56 (01): : 149 - 161
12345