Precision medicine for cancer with next-generation functional diagnostics

被引：0
|
作者：
Adam A. Friedman
Anthony Letai
David E. Fisher
Keith T. Flaherty
机构：
[1] Massachusetts General Hospital Cancer Center,
[2] Harvard Medical School,undefined
[3] Dermatology and Cutaneous Biology Research Center,undefined
[4] Massachusetts General Hospital,undefined
[5] Dana-Farber Cancer Institute,undefined
[6] Harvard Medical School,undefined
来源：
Nature Reviews Cancer | 2015年 / 15卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
Genome-based cancer therapeutic matching is limited by incomplete biological understanding of the relationship between phenotype and cancer genotype. This Opinion article proposes that this limitation can be addressed by functional testing of live patient tumour cells exposed to potential therapies.
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页码：747 / 756
页数：9
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