Mechanisms of drug-induced liver injury: from bedside to bench

被引：0
|
作者：
Shannan Tujios
Robert J. Fontana
机构：
[1] University of Michigan Medical School,Division of Gastroenterology, Department of Internal Medicine
来源：
Nature Reviews Gastroenterology & Hepatology | 2011年 / 8卷
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摘要：
The mechanisms of drug-induced liver injury (DILI) are not well understood. In this Review, the authors propose that a bedside to bench approach involving the study of clinicopathological features of patients with DILI can provide insight into the mechanisms underlying this condition. The authors also discuss the potential role of several factors, including mitochondrial toxicity and the host immune system, in the etiopathogenesis of DILI.
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页码：202 / 211
页数：9
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