N-3-Oxoalkylamides and -Thioamides in the Synthesis of Heterocyclic Compounds. 7. Study of the Cyclization of N-(3-Oxoalkyl)amides of Tosylacetic Acid

被引：0

作者：

A. S. Fisyuk

N. V. Poendaev

机构：

[1] Omsk State University,

来源：

Chemistry of Heterocyclic Compounds | 2003年 / 39卷 / 7期

关键词：

N-(3-oxoalkyl)amides; 2-pyridones; 3-tosyl-3,6-dihydropyridin-2(1H)-ones; intramolecular cyclization;

D O I：

10.1023/A:1026146421293

中图分类号：

学科分类号：

摘要：

Alkyl-substituted N-(3-oxoalkyl)amides of tosylacetic acid are cyclized under the action of bases with the formation of 3-tosyl-3,6-dihydropyridin-2(1H)-ones. In the presence of a phenyl substituent at position C(1) of the 3-oxoalkyl chain the reaction proceeds with the formation of 2-pyridones. The principles influencing the regiodirection of cyclization are explained.

引用

页码：895 / 900

页数：5

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