Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

被引：0

作者：

Maria Pachetti

Bruna Marini

Francesca Benedetti

Fabiola Giudici

Elisabetta Mauro

Paola Storici

Claudio Masciovecchio

Silvia Angeletti

Massimo Ciccozzi

Robert C. Gallo

Davide Zella

Rudy Ippodrino

机构：

[1] Elettra Sincrotrone Trieste - Area Science Park,Department of Physics

[2] University of Trieste,Department of Medicine, Surgery and Health Science

[3] University of Trieste,Institute of Human Virology, Department of Biochemistry and Molecular Biology, School of Medicine

[4] Ulisse BioMed - Area Science Park,Medical Statistic and Molecular Epidemiology Unit

[5] University of Maryland,Institute of Human Virology, Department of Medicine, School of Medicine

[6] University of Biomedical Campus,undefined

[7] University of Maryland,undefined

[8] Co-founder and International Science Advisor - Global Virus Network,undefined

[9] Member of the Global Virus Network,undefined

来源：

Journal of Translational Medicine | / 18卷

关键词：

SARS-CoV-2; COVID-19; Mutation; Drug resistance; RdRp; Europe; RNA-dependent-RNA-polymerase; Pneumonia; Viral mutagenesis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 50 条

[21] The RNA-Dependent-RNA Polymerase, an Emerging Antiviral Drug Target for the Hendra Virus
Velkov, Tony
Carbone, Vincenzo
Akter, Jesmin
Sivanesan, Sivashangarie
Li, Jian
Beddoe, Travis
Marsh, Glenn A.
CURRENT DRUG TARGETS, 2014, 15 (01) : 103 - 113
[22] Electron Density Analysis of SARS-CoV-2 RNA-Dependent RNA Polymerase Complexes
Palko, Nadezhda
Grishina, Maria
Potemkin, Vladimir
MOLECULES, 2021, 26 (13):
[23] Computational Study of SARS-CoV-2 RNA Dependent RNA Polymerase Allosteric Site Inhibition
Faisal, Shah
Badshah, Syed Lal
Kubra, Bibi
Sharaf, Mohamed
Emwas, Abdul-Hamid
Jaremko, Mariusz
Abdalla, Mohnad
MOLECULES, 2022, 27 (01):
[24] Inhibition of the RNA-dependent RNA Polymerase of the SARS-CoV-2 by Short Peptide Inhibitors
Pant, Suyash
Jena, N. R.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 167
[25] The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme
Walker, Alexander P.
Fan, Haitian
Keown, Jeremy R.
Knight, Michael L.
Grimes, Jonathan M.
Fodor, Ervin
NUCLEIC ACIDS RESEARCH, 2021, 49 (22) : 13019 - 13030
[26] Molecular docking, molecular dynamics simulation and MM-GBSA studies of the activity of glycyrrhizin relevant substructures on SARS-CoV-2 RNA-dependent-RNA polymerase
Zamzami, Mazin A.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (05): : 1846 - 1858
[27] RNA polymerase: The Achilles heel of SARS-CoV-2
Corteggiani, Marie
Gombert, Lucas
Pellegri, Callypso
Aussel, Laurent
M S-MEDECINE SCIENCES, 2021, 37 (03): : 288 - 292
[28] Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant
Ilmjaerv, Sten
Abdul, Fabien
Acosta-Gutierrez, Silvia
Estarellas, Carolina
Galdadas, Ioannis
Casimir, Marina
Alessandrini, Marco
Gervasio, Francesco Luigi
Krause, Karl-Heinz
SCIENTIFIC REPORTS, 2021, 11 (01)
[29] Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant
Sten Ilmjärv
Fabien Abdul
Silvia Acosta-Gutiérrez
Carolina Estarellas
Ioannis Galdadas
Marina Casimir
Marco Alessandrini
Francesco Luigi Gervasio
Karl-Heinz Krause
Scientific Reports, 11
[30] Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP
Naydenova, Katerina
Muir, Kyle W.
Wu, Long-Fei
Zhang, Ziguo
Coscia, Francesca
Peet, Mathew J.
Castro-Hartmann, Pablo
Qian, Pu
Sader, Kasim
Dent, Kyle
Kimanius, Dari
Sutherland, John D.
Lowe, Jan
Barford, David
Russo, Christopher J.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (07)

← 1 2 3 4 5 →