Glanzmann's thrombasthenia

被引:5
|
作者
Tullu M.S. [1 ,3 ]
Dixit P.S. [1 ]
Nair S.B. [2 ]
Kamat J.R. [1 ]
Vaswani R.K. [1 ]
Shetty S.D. [2 ]
Pawar A.R. [2 ]
机构
[1] Departments of Pediatrics, Seth G.S. Medical College, KEM Hospital, Parel, Mumbai-400 012, Maharashtra
[2] Inst. of Immunohaematology, Multi-Storied Building, KEM Hospital, Parel, Mumbai-400 012, Maharashtra
[3] Sankalp Siddhi, Mumbai - 400 051, Maharashtra, Kher Nagar, Bandra (East)
关键词
Adenosine diphosphate; Bleeding time; Flow cytometry; Platelet aggregation; Platelet count; Platelet function tests;
D O I
10.1007/BF02723255
中图分类号
学科分类号
摘要
Glanzmann's thrombasthenia (GT) is an uncommon cause of bleeding in children. We diagnosed two siblings as having GT on the basis of flow cytometric studies. Both had cutaneous bleedings and epistaxis since early childhood. Hematological investigations revealed prolonged bleeding time and a normal platelet count. Both the patients had absence of aggregation of platelets with the agonist adenosine diphosphate. Absence of the GPllb/ IIIa receptor was confirmed by flow cytometry. A short review of the disorder is presented.
引用
收藏
页码:563 / 566
页数:3
相关论文
共 50 条
  • [31] Gene analysis of Glanzmann's thrombasthenia in a Japanese
    Tanaka, S
    Ohnoki, S
    Takahashi, J
    Yoshimura, K
    Shibata, H
    Fujita, T
    Nakayama, M
    Amano, T
    [J]. THROMBOSIS AND HAEMOSTASIS, 1997, : P1479 - P1479
  • [32] Colonoscopy polypectomy management in Glanzmann's thrombasthenia
    Raina, Dimple
    Movva, Arvind
    Rahhal, Fadi
    Abderrahim, Khomani
    Schade, Robert
    Chamberlain, Sherman M.
    [J]. WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY, 2009, 1 (01): : 72 - 75
  • [33] Thrombogenic mutations in glanzmann's thrombasthenia patients
    Kannan, M.
    Yadav, B. K.
    Ahmad, F.
    Fareed, J.
    Saxena, R.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 636 - 636
  • [34] Glanzmann thrombasthenia: An update
    Franchini, Massimo
    Favaloro, Emmanuel J.
    Lippi, Giuseppe
    [J]. CLINICA CHIMICA ACTA, 2010, 411 (1-2) : 1 - 6
  • [35] Granules secretion in patients with Glanzmann's thrombasthenia
    Pilgrimm-Thorp, A-K
    Krause, M.
    Pillitteri, D.
    Behrendt, T.
    Kirchmaier, C.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2015, 13 : 659 - 659
  • [36] Endometriosis in two sisters with Glanzmann's thrombasthenia
    Alatas, Erkan
    Oztekin, Ozer
    Hacioglu, Sibel Kabukcu
    [J]. FERTILITY AND STERILITY, 2009, 92 (04) : 1496.e5 - 1496.e8
  • [37] A family with an interesting variant of Glanzmann's thrombasthenia
    Westrup, D.
    Herrmann, S.
    Scholz, T.
    Pillitteri, D.
    Mahnel, R.
    Krause, M.
    Kirchmaier, C. M.
    [J]. HAMOSTASEOLOGIE, 2009, 29 : S110 - S110
  • [38] Platelet function assessment in Glanzmann's thrombasthenia
    Monte, S
    Lyons, G
    [J]. BRITISH JOURNAL OF ANAESTHESIA, 2002, 89 (03)
  • [39] Glanzmann's thrombasthenia with pregnancy: A case report
    Ciantar, Etienne
    Shazly, Sherif
    [J]. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2023, 130 : 86 - 86
  • [40] Platelet dysfunction (Glanzmann's thrombasthenia) in horses
    Livesey, L
    Christopherson, P
    Hammond, A
    Perkins, J
    Toivio-Kinnucan, M
    Insalaco, T
    Boudreaux, MK
    [J]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 2005, 19 (06) : 917 - 919