Glanzmann's thrombasthenia

被引：5
|
作者：
Tullu M.S. [1 ,3 ]
Dixit P.S. [1 ]
Nair S.B. [2 ]
Kamat J.R. [1 ]
Vaswani R.K. [1 ]
Shetty S.D. [2 ]
Pawar A.R. [2 ]
机构：
[1] Departments of Pediatrics, Seth G.S. Medical College, KEM Hospital, Parel, Mumbai-400 012, Maharashtra
[2] Inst. of Immunohaematology, Multi-Storied Building, KEM Hospital, Parel, Mumbai-400 012, Maharashtra
[3] Sankalp Siddhi, Mumbai - 400 051, Maharashtra, Kher Nagar, Bandra (East)
来源：
The Indian Journal of Pediatrics | 2001年 / 68卷 / 6期
关键词：
Adenosine diphosphate; Bleeding time; Flow cytometry; Platelet aggregation; Platelet count; Platelet function tests;
D O I：
10.1007/BF02723255
中图分类号：
学科分类号：
摘要：
Glanzmann's thrombasthenia (GT) is an uncommon cause of bleeding in children. We diagnosed two siblings as having GT on the basis of flow cytometric studies. Both had cutaneous bleedings and epistaxis since early childhood. Hematological investigations revealed prolonged bleeding time and a normal platelet count. Both the patients had absence of aggregation of platelets with the agonist adenosine diphosphate. Absence of the GPllb/ IIIa receptor was confirmed by flow cytometry. A short review of the disorder is presented.
引用
收藏
页码：563 / 566
页数：3
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