Drug Transfer and Metabolism by the Human Placenta

被引：0
|
作者：
Michael R. Syme
James W. Paxton
Jeffrey A. Keelan
机构：
[1] University of Auckland,Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences
来源：
Clinical Pharmacokinetics | 2004年 / 43卷
关键词：
Digoxin; Buprenorphine; Saquinavir; Human Placenta; Maternal Blood;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The major function of the placenta is to transfer nutrients and oxygen from the mother to the foetus and to assist in the removal of waste products from the foetus to the mother. In addition, it plays an important role in the synthesis of hormones, peptides and steroids that are vital for a successful pregnancy. The placenta provides a link between the circulations of two distinct individuals but also acts as a barrier to protect the foetus from xenobiotics in the maternal blood.
引用
收藏
页码：487 / 514
页数：27
相关论文
共 50 条
  • [41] NUCLEIC ACID METABOLISM OF HUMAN PLACENTA
    HAYASHI, TT
    BALDRIDGE, RC
    CLINICAL OBSTETRICS AND GYNECOLOGY, 1963, 6 (01): : 57 - 61
  • [42] The carbohydrate metabolism of human placenta.
    Felix, K
    von Oettingen, K
    HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1925, 144 (3/6): : 190 - 195
  • [43] Metabolism of glibenclamide (glyburide) by human placenta
    Jain, S
    Zharikova, O
    Ravindran, S
    Nanovskaya, T
    Hankins, GDV
    Ahmed, MS
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2005, 193 (06) : S91 - S91
  • [44] Oxygen metabolism in human placenta mitochondria
    J. Bustamante
    R. Ramírez-Vélez
    A. Czerniczyniec
    D. Cicerchia
    A. C. Aguilar de Plata
    S. Lores-Arnaiz
    Journal of Bioenergetics and Biomembranes, 2014, 46 : 459 - 469
  • [45] Oxygen metabolism in human placenta mitochondria
    Bustamante, J.
    Ramirez-Velez, R.
    Czerniczyniec, A.
    Cicerchia, D.
    Aguilar de Plata, A. C.
    Lores-Arnaiz, S.
    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 2014, 46 (06) : 459 - 469
  • [46] METABOLISM OF CHOLESTEROL ESTERS IN HUMAN PLACENTA
    ROBERTSON, AF
    SPRECHER, H
    DOBBS, C
    BIOLOGIA NEONATORUM, 1969, 14 (1-2): : 32 - +
  • [47] Metabolism of synthetic steroids by the human placenta
    Murphy, V. E.
    Fittock, R. J.
    Zarzycki, P. K.
    Delahunty, M. M.
    Smith, R.
    Clifton, V. L.
    PLACENTA, 2007, 28 (01) : 39 - 46
  • [48] EFFECTS OF ESTRADIOL ON THE METABOLISM OF HUMAN PLACENTA
    VILLEE, CA
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1954, 14 (07): : 764 - 764
  • [49] Metabolism of synthetic steroids by the human placenta
    Baehr, V.
    Pfeiffer, A. F. H.
    Oelkers, W.
    Diederich, S.
    Pfeiffer, A. F. H.
    PLACENTA, 2007, 28 (5-6) : 588 - 589
  • [50] Overview of Drug Transporters in Human Placenta
    Yamashita, Michiko
    Markert, Udo R.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (23)
12345