Drug Transfer and Metabolism by the Human Placenta

被引:0
|
作者
Michael R. Syme
James W. Paxton
Jeffrey A. Keelan
机构
[1] University of Auckland,Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences
来源
Clinical Pharmacokinetics | 2004年 / 43卷
关键词
Digoxin; Buprenorphine; Saquinavir; Human Placenta; Maternal Blood;
D O I
暂无
中图分类号
学科分类号
摘要
The major function of the placenta is to transfer nutrients and oxygen from the mother to the foetus and to assist in the removal of waste products from the foetus to the mother. In addition, it plays an important role in the synthesis of hormones, peptides and steroids that are vital for a successful pregnancy. The placenta provides a link between the circulations of two distinct individuals but also acts as a barrier to protect the foetus from xenobiotics in the maternal blood.
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页码:487 / 514
页数:27
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