Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

被引:0
|
作者
Antony V. Samrot
Tatipamula Akanksha
S. Jahnavi
Sheryl-Ann Padmanaban
Ujjala Philip
Arul Maximus Burman
机构
[1] Sathyabama University,Department of Biotechnology
来源
Applied Nanoscience | 2016年 / 6卷
关键词
Chitosan (CS); Carboxymethyl cellulose (CMC); Sodium tripolyphosphate (TPP); Barium chloride;
D O I
暂无
中图分类号
学科分类号
摘要
In this study, polyphenolic curcumin is entrapped within microcomposites made of biopolymers chitosan (CS) and carboxymethyl cellulose (CMC) formulated by ionic gelation method. Here, different concentrations of two chelating agents, barium chloride and sodium tripolyphosphate, are used to make microcomposites. Thus, the synthesized microparticles were characterized by FTIR, and their surface morphology was studied by SEM. Drug encapsulation efficiency and the drug release kinetics of CS–CMC composites are also studied. The produced microcomposites were used to study antibacterial activity in vitro.
引用
收藏
页码:1219 / 1231
页数:12
相关论文
共 50 条
  • [41] Development and in vitro evaluation of carboxymethyl chitosan based drug delivery system for the controlled release of propranolol hydrochloride
    Hernawan
    Hayati, Septi Nur
    Nisa, Khoirun
    Indrianingsih, Anastasia Wheni
    Darsih, Cici
    Kismurtono, Muhammad
    [J]. INTERNATIONAL CONFERENCE ON NATURAL PRODUCTS AND BIORESOURCE SCIENCE 2017 (ICONPROBIOS 2017), 2017, 101
  • [42] MUCOADHESIVE MICROPARTICLES OF CARBOXYMETHYL CHITOSAN FOR SITE SPECIFIC DELIVERY OF PANTOPRAZOLE: FORMULATION AND IN VITRO CHARACTERIZATION
    Gujarathi, N. A.
    Rane, B. R.
    Patel, J. K.
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (11): : 4314 - 4321
  • [43] Synthesis and Characterization of Carboxymethyl Cellulose/β-Cyclodextrin/Chitosan Hydrogels and Investigating the Effect of Magnetic Nanoparticles (Fe3O4) on a Novel Carrier for a Controlled Release of Methotrexate as Drug Delivery
    Zahra Naderi
    Javad Azizian
    Elham Moniri
    Nazanin Farhadyar
    [J]. Journal of Inorganic and Organometallic Polymers and Materials, 2020, 30 : 1339 - 1351
  • [44] Synthesis and Characterization of Carboxymethyl Cellulose/β-Cyclodextrin/Chitosan Hydrogels and Investigating the Effect of Magnetic Nanoparticles (Fe3O4) on a Novel Carrier for a Controlled Release of Methotrexate as Drug Delivery
    Naderi, Zahra
    Azizian, Javad
    Moniri, Elham
    Farhadyar, Nazanin
    [J]. JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2020, 30 (04) : 1339 - 1351
  • [45] Topical drug delivery using chitosan nano- and microparticles
    Sezer, Ali Demir
    Cevher, Erdal
    [J]. EXPERT OPINION ON DRUG DELIVERY, 2012, 9 (09) : 1129 - 1146
  • [46] Thiolated chitosan microparticles:: A vehicle for nasal peptide drug delivery
    Krauland, AH
    Guggi, D
    Bernkop-Schnürch, A
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2006, 307 (02) : 270 - 277
  • [47] Tailored-interpenetrating polymer network beads of κ-carrageenan and sodium carboxymethyl cellulose for controlled drug delivery
    Lohani, Alka
    Singh, Garima
    Bhattacharya, Shiv Sankar
    Hegde, Rahul Rama
    Verma, Anurag
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2016, 31 : 53 - 64
  • [48] CELL 138-Conjugation of chemotherapeutics to carboxymethyl cellulose as a potential system for drug delivery and controlled release
    Dennis, Maren L.
    Knihnicky, Alexander
    Martey-Ochola, Christine A.
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
  • [49] Preparation and characterization of pH-sensitive carboxymethyl cellulose-based hydrogels for controlled drug delivery
    Pourkhatoun, Mina
    Kalantari, Maryam
    Kamyabi, Ata
    Moradi, Ali
    [J]. POLYMER INTERNATIONAL, 2022, 71 (08) : 991 - 998
  • [50] Chitosan-clay nanocomposite microparticles for controlled drug delivery: Effects of the MAS content and TPP crosslinking
    Khlibsuwan, Rapee
    Siepmann, Florence
    Siepmann, Juergen
    Pongjanyakul, Thaned
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2017, 40 : 1 - 10