Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

被引：0
|
作者：
Antony V. Samrot
Tatipamula Akanksha
S. Jahnavi
Sheryl-Ann Padmanaban
Ujjala Philip
Arul Maximus Burman
机构：
[1] Sathyabama University,Department of Biotechnology
来源：
Applied Nanoscience | 2016年 / 6卷
关键词：
Chitosan (CS); Carboxymethyl cellulose (CMC); Sodium tripolyphosphate (TPP); Barium chloride;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this study, polyphenolic curcumin is entrapped within microcomposites made of biopolymers chitosan (CS) and carboxymethyl cellulose (CMC) formulated by ionic gelation method. Here, different concentrations of two chelating agents, barium chloride and sodium tripolyphosphate, are used to make microcomposites. Thus, the synthesized microparticles were characterized by FTIR, and their surface morphology was studied by SEM. Drug encapsulation efficiency and the drug release kinetics of CS–CMC composites are also studied. The produced microcomposites were used to study antibacterial activity in vitro.
引用
收藏
页码：1219 / 1231
页数：12
相关论文
共 50 条
  • [21] Synthesis and characterization of polysialic acid/carboxymethyl chitosan hydrogel with potential for drug delivery
    J. R. Wu
    X. B. Zhan
    Z. Y. Zheng
    H. T. Zhang
    [J]. Russian Journal of Bioorganic Chemistry, 2015, 41 : 562 - 567
  • [22] Carboxymethyl β-cyclodextrin grafted carboxymethyl chitosan hydrogel-based microparticles for oral insulin delivery
    Yang, Yu
    Liu, Yang
    Chen, Shengqin
    Cheong, Kit-Leong
    Teng, Bo
    [J]. CARBOHYDRATE POLYMERS, 2020, 246
  • [23] Cross-linked β-cyclodextrin and carboxymethyl cellulose hydrogels for controlled drug delivery of acyclovir
    Malik, Nadia Shamshad
    Ahmad, Mahmood
    Minhas, Muhammad Usman
    [J]. PLOS ONE, 2017, 12 (02):
  • [24] Synthesis of oxidized carboxymethyl cellulose/chitosan hydrogels doped with graphene oxide for pH- and NIR-responsive drug delivery
    Zhao, Zherui
    Gao, Jun
    Cai, Wenrong
    Li, Junyao
    Kong, Yong
    Zhou, Min
    [J]. EUROPEAN POLYMER JOURNAL, 2023, 199
  • [25] Novel Carboxymethyl Chitosan Microspheres for Controlled Delivery of Chelerythrine
    Li, Gui-Yin
    Zhong, Ming
    Zhou, Zhi-De
    Ding, Ping
    Li, Yuan-Jian
    [J]. JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2011, 48 (11): : 904 - 911
  • [26] Drug delivery based on chitosan, β-cyclodextrin and sodium carboxymethyl cellulose as well as nanocarriers for advanced leukemia treatment
    Hosseini, Melika
    Amiri, Mahnaz
    Ghanbari, Mojgan
    Mahdi, Makarim A.
    Abdulsahib, Waleed K.
    Salavati-Niasari, Masoud
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2022, 153
  • [27] Carboxymethyl-Cellulose-Based Hydrogels Incorporated with Cellulose Nanocrystals Loaded with Vitamin D for Controlled Drug Delivery
    Silva, Nathalia da Cunha
    Silva, Carla Jeany Teixeira
    Goncalves, Max Pereira
    Borsagli, Fernanda G. L. Medeiros
    [J]. PROCESSES, 2024, 12 (07)
  • [28] Chitosan Microparticles for Drug Delivery against Dental Caries
    Kumar, Khandelwal Amit
    Shweta, Bisht
    Kumar, Arya Rahul
    Sumit, Kharbanda
    Pratap, Singh Sujeet
    [J]. RESEARCH JOURNAL OF BIOTECHNOLOGY, 2020, 15 (07): : 26 - 36
  • [29] Graft copolymers of carboxymethyl cellulose with N-vinylimidazole: synthesis and application for drug delivery
    Vyacheslav A. Kuznetsov
    Andrey V. Sorokin
    Maria S. Lavlinskaya
    Alexander A. Sinelnikov
    Dmitriy V. Bykovskiy
    [J]. Polymer Bulletin, 2019, 76 : 4929 - 4949
  • [30] Graft copolymers of carboxymethyl cellulose with N-vinylimidazole: synthesis and application for drug delivery
    Kuznetsov, Vyacheslav A.
    Sorokin, Andrey V.
    Lavlinskaya, Maria S.
    Sinelnikov, Alexander A.
    Bykovskiy, Dmitriy V.
    [J]. POLYMER BULLETIN, 2019, 76 (10) : 4929 - 4949
12345