Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson’s disease mutant of Leucine-rich repeat kinase 2 (LRRK2)

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作者
Radek Linhart
Sarah Anne Wong
Jieyun Cao
Melody Tran
Anne Huynh
Casey Ardrey
Jong Min Park
Christine Hsu
Saher Taha
Rentia Peterson
Shannon Shea
Jason Kurian
Katerina Venderova
机构
[1] University of the Pacific,Department of Physiology and Pharmacology, Thomas J. Long School of Pharmacy and Health Sciences
关键词
Parkinson’s disease; LRRK2; VPS35; Retromer; Endolysosomal pathway; Drosophila; Genetics; Rotenone; Neurodegeneration; Endosomes; Lysosome; VPS26;
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