Hybrid enhanced sampling approaches to gain structural insights into leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease mutation

被引：0
|
作者：
Ojha, Anupam A. [1 ]
Amaro, Rommie E. [1 ]
机构：
[1] Univ Calif San Diego, Chem & Biochem, San Diego, CA USA
来源：
BIOPHYSICAL JOURNAL | 2023年 / 122卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
913-Pos
引用
收藏
页码：187A / 187A
页数：1
相关论文
共 50 条
  • [1] The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
    Cookson, Mark R.
    NATURE REVIEWS NEUROSCIENCE, 2010, 11 (12) : 791 - 797
  • [2] The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
    Mark R. Cookson
    Nature Reviews Neuroscience, 2010, 11 : 791 - 797
  • [3] Targeting leucine-rich repeat kinase 2 (LRRK2) for the treatment of Parkinson's disease
    Domingos, Sofia
    Duarte, Teresa
    Saraiva, Lucilia
    Guedes, Rita C.
    Moreira, Rui
    FUTURE MEDICINAL CHEMISTRY, 2019, 11 (15) : 1953 - 1977
  • [4] Function and dysfunction of leucine-rich repeat kinase 2 (LRRK2): Parkinson's disease and beyond
    Bae, Jae Ryul
    Lee, Byoung Dae
    BMB REPORTS, 2015, 48 (05) : 243 - 248
  • [5] Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease
    Lee, Byoung Dae
    Dawson, Valina L.
    Dawson, Ted M.
    TRENDS IN PHARMACOLOGICAL SCIENCES, 2012, 33 (07) : 365 - 373
  • [6] Genetic characteristics of leucine-rich repeat kinase 2 (LRRK2) associated Parkinson's disease
    Bardien, Soraya
    Lesage, Suzanne
    Brice, Alexis
    Carr, Jonathan
    PARKINSONISM & RELATED DISORDERS, 2011, 17 (07) : 501 - 508
  • [7] Leucine-Rich Repeat Kinase 2 (LRRK2): A Key Player in the Pathogenesis of Parkinson's Disease
    Gandhi, Payal N.
    Chen, Shu G.
    Wilson-Delfosse, Amy L.
    JOURNAL OF NEUROSCIENCE RESEARCH, 2009, 87 (06) : 1283 - 1295
  • [8] Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson’s disease
    Julie P. Taylor
    Mary M. Hulihan
    Jennifer M. Kachergus
    Heather L. Melrose
    Sarah J. Lincoln
    Kelly M. Hinkle
    Jeremy T. Stone
    Owen A. Ross
    Robert Hauser
    Jan Aasly
    Thomas Gasser
    Haydeh Payami
    Zbigniew K. Wszolek
    Matthew J. Farrer
    Neurogenetics, 2007, 8 : 95 - 102
  • [9] Inhibitors of Leucine-Rich Repeat Kinase 2 (LRRK2): Progress and Promise for the Treatment of Parkinson's Disease
    Gilligan, Paul J.
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2015, 15 (10) : 927 - 938
  • [10] Leucine-rich repeat kinase 2 (LRRK2): an update on the potential therapeutic target for Parkinson's disease
    Kluss, Jillian H.
    Lewis, Patrick A.
    Greggio, Elisa
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2022, 26 (06) : 537 - 546
12345