Thiopurine S-methyltransferase activity in human erythrocytes: a new HPLC method using 6-thioguanine as substrate

被引:0
|
作者
T. Kröplin
N. Weyer
S. Gutsche
H. Iven
机构
[1] Department of Pharmacology,
[2] Lübeck Medical University,undefined
[3] Ratzeburger Allee 160,undefined
[4] D-23538 Lübeck,undefined
[5] Germany Tel. +49-451-500 2682; Fax +49-451-500 2686,undefined
关键词
Key words Thiopurine methyltransferase; Polymorphism;
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中图分类号
学科分类号
摘要
Objectives: To develop a non-radioactive assay to measure thiopurine S-methyltransferase (TPMT) activity. The assay was used to study the distribution of TPMT activity in a healthy German population.
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页码:265 / 271
页数:6
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