HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

被引：0

作者：

Sonja I Gringhuis

Michiel van der Vlist

Linda M van den Berg

Jeroen den Dunnen

Manja Litjens

Teunis B H Geijtenbeek

机构：

[1] Center for Experimental and Molecular Medicine,Department of Molecular Cell Biology and Immunology

[2] Academic Medical Center,undefined

[3] University of Amsterdam,undefined

[4] VU University Medical Center,undefined

[5] Present address: Cell Biology and Histology,undefined

[6] Academic Medical Center,undefined

[7] University of Amsterdam,undefined

[8] Amsterdam,undefined

[9] The Netherlands.,undefined

来源：

Nature Immunology | 2010年 / 11卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

HIV-1 replication requires proviral production of full-length transcripts. Geijtenbeek and colleagues show that early Tat-independent HIV-1 replication coopts innate receptor signaling by DC-SIGN and TLR8 to promote RNA polymerase II elongation complexes at long terminal repeats.

引用

页码：419 / 426

页数：7

共 50 条

[31] Sensing of HIV-1 nucleic acids by TLR8 in human CD4+T cells
Haug, M.
Meas, H. Z.
Beckwith, Sandvold M.
Louet, C.
Ryan, L.
Hu, Z.
Landskron, J.
Nordbo, S. A.
Tasken, K.
Yin, H. H.
Damas, J. K.
Flo, T. H.
EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1053 - 1054
[32] Novel HIV-1 MiRNAs Stimulate TNFα Release in Human Macrophages via TLR8 Signaling Pathway
Bernard, Mark A.
Zhao, Hui
Yue, Simon C.
Anandaiah, Asha
Koziel, Henry
Tachado, Souvenir D.
PLOS ONE, 2014, 9 (09):
[33] Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells
Smith, Alvin L.
Ganesh, Lakshmanan
Leung, Kwanyee
Jongstra-Bilen, Jenny
Jongstra, Jan
Nabel, Gary J.
JOURNAL OF EXPERIMENTAL MEDICINE, 2007, 204 (02): : 421 - 430
[34] DC-sign, a novel dendritic cell-specific adhesion receptor for ICAM-3 mediates DC-T cell interactions and HIV-1 infection of DC.
Geijtenbeek, TBH
Torensma, R
van Vliet, SJ
van Duijnhoven, GCF
Middel, J
Cornelissen, ILMHA
Adema, GJ
Nottet, HSLM
Figdor, CG
van Kooyk, Y
BLOOD, 1999, 94 (10) : 434A - 434A
[35] DC-SIGN-mediated transfer of HIV-1 is compromised by the ability of Leishmania infantum to exploit DC-SIGN as a ligand
Zhao, CQ
Cantin, R
Breton, M
Papadopoulou, B
Tremblay, MJ
JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (10): : 1665 - 1669
[36] DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells
Tassaneetrithep, B
Burgess, TH
Granelli-Piperno, A
Trumpfherer, C
Finke, J
Sun, W
Eller, MA
Pattanapanyasat, K
Sarasombath, S
Birx, DL
Steinman, RM
Schlesinger, S
Marovich, MA
JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (07): : 823 - 829
[37] DENDRITIC CELLS IN THE PATHOGENESIS OF HIV-1 INFECTION
KNIGHT, SC
PATTERSON, S
REVIEWS IN MEDICAL VIROLOGY, 1995, 5 (03) : 133 - 139
[38] Myeloid dendritic cells in HIV-1 infection
Derby, Nina
Martinelli, Elena
Robbiani, Melissa
CURRENT OPINION IN HIV AND AIDS, 2011, 6 (05) : 379 - 384
[39] Treating HIV-1 infection with dendritic cells
Connolly, Nancy C.
Colleton, Bonnie A.
Rinaldo, Charles R.
CURRENT OPINION IN MOLECULAR THERAPEUTICS, 2007, 9 (04) : 353 - 363
[40] Binding of HIV-1 gp120 to DC-SIGN Promotes ASK-1-Dependent Activation-Induced Apoptosis of Human Dendritic Cells
Chen, Yongxiong
Hwang, Shiuh-Lin
Chan, Vera S. F.
Chung, Nancy P. Y.
Wang, Shu-Rong
Li, Zhongye
Ma, Jing
Lin, Chia-Wei
Hsieh, Ya-Ju
Chang, Kao-Ping
Kung, Sui-Sum
Wu, Yi-Chia
Chu, Cheng-Wei
Tai, Hsiao-Ting
Gao, George F.
Zheng, Bojian
Yokoyama, Kazunari K.
Austyn, Jonathan M.
Lin, Chen-Lung S.
PLOS PATHOGENS, 2013, 9 (01)

← 1 2 3 4 5 →