Biologic agents in experimental autoimmune uveitis

被引：0
|
作者：
Gian Paolo Giuliari
Ama Sadaka
David M. Hinkle
机构：
[1] Centro de Cirugía Oftalmológica (CECOF),Department of Ophthalmology
[2] School of Medicine,undefined
[3] Domingo Luciani Hospital,undefined
[4] Universidad Central de Venezuela,undefined
[5] Trihealth’s Good Samaritan Hospital,undefined
[6] Albany Retina Consultants PLLC,undefined
来源：
International Ophthalmology | 2014年 / 34卷
关键词：
Autoimmune experimental uveitis; Biologic agents; Cytokines; Autoimmune disease; Immunosuppression;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Experimental uveitis models were developed in an effort to elucidate the pathogenesis of human uveitis. The therapeutic effects of numerous anti-inflammatory agents including corticosteroids and immunomodulatory agents including biologic response modifiers have been investigated in both experimental and human uveitis. Monoclonal antibodies to tumor necrosis factor alpha and anti-interleukins, among others, demonstrate efficacy and are employed in the treatment of uveitis refractory to conventional immunomodulatory agents.
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页码：145 / 156
页数：11
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