Biologic agents in experimental autoimmune uveitis

被引：0

作者：

Gian Paolo Giuliari

Ama Sadaka

David M. Hinkle

机构：

[1] Centro de Cirugía Oftalmológica (CECOF),Department of Ophthalmology

[2] School of Medicine,undefined

[3] Domingo Luciani Hospital,undefined

[4] Universidad Central de Venezuela,undefined

[5] Trihealth’s Good Samaritan Hospital,undefined

[6] Albany Retina Consultants PLLC,undefined

来源：

International Ophthalmology | 2014年 / 34卷

关键词：

Autoimmune experimental uveitis; Biologic agents; Cytokines; Autoimmune disease; Immunosuppression;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Experimental uveitis models were developed in an effort to elucidate the pathogenesis of human uveitis. The therapeutic effects of numerous anti-inflammatory agents including corticosteroids and immunomodulatory agents including biologic response modifiers have been investigated in both experimental and human uveitis. Monoclonal antibodies to tumor necrosis factor alpha and anti-interleukins, among others, demonstrate efficacy and are employed in the treatment of uveitis refractory to conventional immunomodulatory agents.

引用

页码：145 / 156

页数：11

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