Construction and destruction of MHC class I in the peptide-loading complex

被引:0
|
作者
Gianna E Hammer
Nilabh Shastri
机构
[1] University of California,Gianna E. Hammer and Nilabh Shastri are in the Division of Immunology, Department of Molecular and Cell Biology
[2] Berkeley,undefined
[3] California 94720-3200,undefined
[4] USA. nshastri@berkeley.edu,undefined
来源
Nature Immunology | 2007年 / 8卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Tapasin enhances the loading and editing of peptide 'cargo' onto major histocompatibility complex class I molecules, yet it cannot do so alone. Two new reports show that the oxidoreductase ERp57 assists tapasin in these activities.
引用
收藏
页码:793 / 794
页数:1
相关论文
共 50 条
  • [31] Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading complex
    Peaper, DR
    Wearsch, PA
    Cresswell, P
    EMBO JOURNAL, 2005, 24 (20): : 3613 - 3623
  • [32] Viral proteins interfering with antigen presentation target the major histocompatibility complex class I peptide-loading complex
    Roder, Gustav
    Geironson, Linda
    Bressendorff, Iain
    Paulsson, Kajsa
    JOURNAL OF VIROLOGY, 2008, 82 (17) : 8246 - 8252
  • [33] Entry of Ig alpha and Ig beta to the MHC class II peptide-loading compartment
    Song, WX
    Brown, BK
    MOLECULAR BIOLOGY OF THE CELL, 1997, 8 : 2459 - 2459
  • [34] Molecular architecture of the MHC I peptide-loading complex: one tapasin molecule is essential and sufficient for antigen processing
    Hulpke, Sabine
    Baldauf, Christoph
    Tampe, Robert
    FASEB JOURNAL, 2012, 26 (12): : 5071 - 5080
  • [35] Major histocompatibility complex class I-ERp57-tapasin interactions within the peptide-loading complex
    Santos, Susana G.
    Campbell, Elaine C.
    Lynch, Sarah
    Wong, Vincent
    Antoniou, Antony N.
    Powis, Simon J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (24) : 17587 - 17593
  • [36] Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex
    Sethumadhavan, Sunesh
    Barth, Marie
    Spaapen, Robbert M.
    Schmidt, Carla
    Trowitzsch, Simon
    Tampe, Robert
    SCIENTIFIC REPORTS, 2022, 12 (01)
  • [37] The quality control of MHC class I peptide loading
    Wearsch, Pamela A.
    Cresswell, Peter
    CURRENT OPINION IN CELL BIOLOGY, 2008, 20 (06) : 624 - 631
  • [38] Peptide loading of nascent MHC class I molecules
    Vukmanovic, S
    Lilic, M
    Santori, FR
    Demaria, S
    Kulig, K
    ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2001, 49 (03) : 195 - 201
  • [39] Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex
    Sunesh Sethumadhavan
    Marie Barth
    Robbert M. Spaapen
    Carla Schmidt
    Simon Trowitzsch
    Robert Tampé
    Scientific Reports, 12
  • [40] Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription
    Halenius, Anne
    Hauka, Sebastian
    Doelken, Lars
    Stindt, Jan
    Reinhard, Henrike
    Wiek, Constanze
    Hanenberg, Helmut
    Koszinowski, Ulrich H.
    Momburg, Frank
    Hengel, Hartmut
    JOURNAL OF VIROLOGY, 2011, 85 (07) : 3473 - 3485